The relationship between cancer and paraoxonase 1

IM Medina-Díaz, N Ponce-Ruíz, AE Rojas-García… - Antioxidants, 2022 - mdpi.com
Extensive research has been carried out to understand and elucidate the mechanisms of
paraoxonase 1 (PON1) in the development of diseases including cancer, cardiovascular …

Effect of carotenoids on paraoxonase-1 activity and gene expression

A Otocka-Kmiecik - Nutrients, 2022 - mdpi.com
Paraoxonase 1 (PON1) is an antioxidant enzyme attached to HDL with an anti-atherogenic
potential. It protects LDL and HDL from lipid peroxidation. The enzyme is sensitive to various …

[PDF][PDF] Distinct hepatic gene‐expression patterns of NAFLD in patients with obesity

S Subudhi, HK Drescher, LE Dichtel… - Hepatology …, 2022 - Wiley Online Library
Approaches to manage nonalcoholic fatty liver disease (NAFLD) are limited by an
incomplete understanding of disease pathogenesis. The aim of this study was to identify …

Cytokines, miRNAs, and antioxidants as combined non-invasive biomarkers for Parkinson's disease

A Ghit, HE Deeb - Journal of Molecular Neuroscience, 2022 - Springer
Parkinson's disease (PD) is one of the most common long-term degenerative disorders of
the CNS that primarily affects the human locomotor system. Owing to the heterogeneity of …

Lower paraoxonase 1 paraoxonase activity is associated with a worse prognosis in patients with non-ST-segment elevation myocardial infarction in long-term follow …

PCL Leocádio, AC Goulart, IS Santos… - Coronary artery …, 2022 - journals.lww.com
Background Acute coronary syndrome (ACS) is one of the main manifestations of coronary
artery disease, with a higher prevalence and worst prognosis. Oxidative stress is important …

Serum paraoxonase-1 activity and the risk of prostate cancer recurrence in patients treated with radiotherapy

M Jasinski, D Olszewska-Slonina - Antioxidants, 2022 - mdpi.com
The antioxidant paraoxonase-1 (PON1) may be involved in the response to radiation-
induced oxidative stress and possibly prevent cell apoptosis. The correlation of PON1 with …

Paraoxonase 2 is an ER chaperone that regulates the epithelial Na+ channel

S Shi, TM Buck, AJ Nickerson… - … of Physiology-Cell …, 2022 - journals.physiology.org
The mammalian paraoxonases (PONs) have been linked to protection against oxidative
stress. However, the physiological roles of members in this family (PON1, PON2, and PON3) …

Paraoxonase-1 Concentrations in Obstructive Sleep Apnoea: A Systematic Review and Meta-Analysis

MC Pau, A Zinellu, E Zinellu, G Pintus, C Carru… - Antioxidants, 2022 - mdpi.com
Obstructive sleep apnoea (OSA) is characterized by overproduction of reactive oxygen
species and oxidative stress. The antioxidant enzyme paraoxonase-1 (PON-1) may be …

Paraoxonase 1 activity in the sperm-rich portion of boar ejaculates is positively associated with sperm quality

MS Lucca, KL Goularte, MT Rovani, A Schneider… - Animal …, 2022 - SciELO Brasil
Associations of the activity of the paraoxonase 1 (PON1) enzyme with boar sperm quality still
needs to be characterized, since boar ejaculates present distinct portions with differences in …

Mechanism of chlorpyrifos induced chronic nephrotoxicity

S Aung, NZ Abdullah, ZM Zainone - IIUM Medical Journal …, 2022 - journals.iium.edu.my
INTRODUCTION: Chlorpyrifos is one of the most commonly used organophosphates in
agriculture. Report on animal models of chronically exposed chlorpyrifos showed significant …