[HTML][HTML] Enzymatic dispersion of biofilms: An emerging biocatalytic avenue to combat biofilm-mediated microbial infections

R Ramakrishnan, AK Singh, S Singh… - Journal of Biological …, 2022 - ASBMB
Drug resistance by pathogenic microbes has emerged as a matter of great concern to
mankind. Microorganisms such as bacteria and fungi employ multiple defense mechanisms …

[HTML][HTML] Antimicrobial peptides controlling resistant bacteria in animal production

G Rodrigues, L Souza Santos, OL Franco - Frontiers in Microbiology, 2022 - frontiersin.org
In the last few decades, antimicrobial resistance (AMR) has been a worldwide concern. The
excessive use of antibiotics affects animal and human health. In the last few years, livestock …

Lactoferricins impair the cytosolic membrane of Escherichia coli within a few seconds and accumulate inside the cell

EF Semeraro, L Marx, J Mandl, I Letofsky-Papst… - Elife, 2022 - elifesciences.org
We report the real-time response of Escherichia coli to lactoferricin-derived antimicrobial
peptides (AMPs) on length scales bridging microscopic cell sizes to nanoscopic lipid …

Antibacterial peptide encapsulation and sustained release from chitosan-based delivery system

M Zhu, X Hu, H Liu, J Tian, J Yang, L Li, B Luo… - European Polymer …, 2022 - Elsevier
Antimicrobial peptides (AMPs) are a class of short polypeptides that are considered to be
attractive future alternatives to traditional antibiotics for their wide sources, excellent …

[HTML][HTML] Antibacterial efficacy and possible mechanism of action of 2-hydroxyisocaproic acid (HICA)

ASNW Pahalagedara, S Flint, J Palmer, G Brightwell… - PLoS …, 2022 - journals.plos.org
The exploitation of natural antimicrobial compounds that can be used in food preservation
has been fast tracked by the development of antimicrobial resistance to existing …

[HTML][HTML] Bioselectivity of silk protein-based materials and their bio-inspired applications

H Bargel, VT Trossmann, C Sommer… - Beilstein Journal of …, 2022 - beilstein-journals.org
Adhesion to material surfaces is crucial for almost all organisms regarding subsequent
biological responses. Mammalian cell attachment to a surrounding biological matrix is …

Rational design of a trypanocidal peptide derived from Dinoponera quadriceps venom

ML Monteiro, DB Lima, KA Freire, CN Pedron… - European Journal of …, 2022 - Elsevier
Chagas disease is caused by the parasite Trypanosoma cruzi and affects millions of people
worldwide, having no effective cure. The main sanitary emergency is related to patients with …

Hybrid Hydrogels of FKF-Peptide Assemblies and Gelatin for Sustained Antimicrobial Activity

S Dahan, P Aibinder, B Khalfin… - ACS Biomaterials …, 2022 - ACS Publications
The growing resistance of pathogenic bacteria to conventional antibiotics promotes the
development of new antimicrobial agents, including peptides. Hydrogels composed of …

The Remarkable Innate Resistance of Burkholderia bacteria to Cationic Antimicrobial Peptides: Insights into the Mechanism of AMP Resistance

J Ghimire, S Guha, BJ Nelson, LA Morici… - The Journal of …, 2022 - Springer
Gram-negative bacteria belonging to the genus Burkholderia are remarkably resistant to
broad-spectrum, cationic, antimicrobial peptides (AMPs). It has been proposed that this …

[HTML][HTML] Membrane-active antibacterial agents based on calix [4] arene derivatives: synthesis and biological evaluation

S Fang, YY Dang, H Li, H Li, J Liu, R Zhong… - Frontiers in …, 2022 - frontiersin.org
Bacteria have developed increasing resistance to currently used antimicrobial agents. New
classes of antimicrobial drugs are urgently required to fight drug-resistant pathogens. Here …