Protective role of mitochondrial uncoupling proteins against age-related oxidative stress in type 2 diabetes mellitus

M Čater, LK Bombek - Antioxidants, 2022 - mdpi.com
The accumulation of oxidative damage to DNA and other biomolecules plays an important
role in the etiology of aging and age-related diseases such as type 2 diabetes mellitus …

The role and regulatory mechanism of brown adipose tissue activation in diet-induced thermogenesis in health and diseases

PC Chan, PS Hsieh - International journal of molecular sciences, 2022 - mdpi.com
Brown adipose tissue (BAT) has been considered a vital organ in response to non-shivering
adaptive thermogenesis, which could be activated during cold exposure through the …

The non-modifiable factors age, gender, and genetics influence resistance exercise

C Viecelli, CY Ewald - Frontiers in Aging, 2022 - frontiersin.org
Muscle mass and force are key for movement, life quality, and health. It is well established
that resistance exercise is a potent anabolic stimulus increasing muscle mass and force. The …

Normal Thermostability of p. Ser113Leu and p. Arg631Cys Variants of Mitochondrial Carnitine Palmitoyltransferase II (CPT II) in Human Muscle Homogenate

PR Joshi, M Gräfin zu Stolberg-Stolberg, LM Scholle… - Metabolites, 2022 - mdpi.com
Previous fibroblast and recombinant enzyme studies showed a markedly thermolabile p.
Ser113Leu variant compared to the wild-type (WT) in muscle carnitine palmitoyltransferase II …

Skeletal Muscle Uncoupling Proteins in Mice Models of Obesity

L Križančić Bombek, M Čater - Metabolites, 2022 - mdpi.com
Obesity and accompanying type 2 diabetes are among major and increasing worldwide
problems that occur fundamentally due to excessive energy intake during its expenditure …