Red cell transfusion thresholds for preterm infants: finally some answers

EF Bell - Archives of Disease in Childhood-Fetal and Neonatal …, 2022 - fn.bmj.com
Extremely low birthweight infants become anaemic during their care in the neonatal
intensive care unit because of the physiological anaemia experienced by all newborn …

[HTML][HTML] Thresholds for blood transfusion in extremely preterm infants: a review of the latest evidence from two large clinical trials

MP Meyer, KL O'Connor, JH Meyer - Frontiers in Pediatrics, 2022 - frontiersin.org
There are two recently completed large randomized clinical trials of blood transfusions in the
preterm infants most at risk of requiring them. Liberal and restrictive strategies were …

[HTML][HTML] Transfusion-free survival predicts severe retinopathy in preterm neonates

L Teofili, P Papacci, M Bartolo, A Molisso… - Frontiers in …, 2022 - frontiersin.org
Repeated red blood cell (RBC) transfusions are thought to increase the risk for retinopathy
of prematurity (ROP), likely due to a critical fetal hemoglobin (HbF) reduction. In this study …

BORN study: a multicenter randomized trial investigating cord blood red blood cell transfusions to reduce the severity of retinopathy of prematurity in extremely low …

L Teofili, P Papacci, N Orlando, M Bianchi, T Pasciuto… - Trials, 2022 - Springer
Background Extremely low gestational age neonates (ELGANs, ie, neonates born before 28
weeks of gestation) are at high risk of developing retinopathy of prematurity (ROP), with …

Perioperative pediatric erythrocyte transfusions: incorporating hemoglobin thresholds and physiologic parameters in decision-making

LA Downey, SM Goobie - Anesthesiology, 2022 - pubs.asahq.org
This article presents current literature and scientific evidence on hemoglobin thresholds and
physiologic parameters to guide decisions regarding perioperative erythrocyte transfusions …

Regional tissue oxygenation and conventional indicators of red blood cell transfusion in anaemic preterm infants

GKK Low, RKH Nanan - EClinicalMedicine, 2022 - thelancet.com
Background It is unresolved whether low haemoglobin (Hb) and symptoms of anaemia
reflect oxygen delivery-consumption imbalances (fractional tissue oxygen extraction [FTOE]) …

Optimizing fresh-frozen plasma transfusion in surgical neonates through thromboelastography: a quality improvement study

G Raffaeli, N Pesenti, G Cavallaro, V Cortesi… - European Journal of …, 2022 - Springer
Fresh frozen plasma (FFP) is largely misused in the neonatal setting. The aim of the study is
to evaluate the impact of a Thromboelastography (TEG)-based Quality Improvement (QI) …

Immunologic effects of red blood cell and platelet transfusions in neonates

P Davenport, M Sola-Visner - Current opinion in hematology, 2022 - journals.lww.com
Immunologic effects of red blood cell and platelet transfusi... : Current Opinion in Hematology
Immunologic effects of red blood cell and platelet transfusions in neonates : Current Opinion in …

Regional oxygenation and perfusion monitoring to optimize neonatal packed red blood cell transfusion practices: a systematic review

P Jani, K Balegarvirupakshappa, JE Moore… - Transfusion Medicine …, 2022 - Elsevier
Contemporary packed red blood cell transfusion practices in anaemic preterm infants are
primarily based on measurement of hemoglobin or haematocrit. In neonatal intensive care …

Neonatal anemia relates to intestinal injury in preterm infants

WS Kalteren, AF Bos, W van Oeveren… - Pediatric …, 2022 - nature.com
Background Anemia is associated with decreased tissue oxygenation in preterm infants and
may contribute to developing necrotizing enterocolitis (NEC). We aimed to investigate …