[HTML][HTML] Antibody-Dependent Enhancement (ADE) and the role of complement system in disease pathogenesis
Antibody-dependent enhancement (ADE) has been associated with severe disease
outcomes in several viral infections, including respiratory infections. In vitro and in vivo …
outcomes in several viral infections, including respiratory infections. In vitro and in vivo …
New insights into the role of the complement system in human viral diseases
E Ostrycharz, B Hukowska-Szematowicz - Biomolecules, 2022 - mdpi.com
The complement system (CS) is part of the human immune system, consisting of more than
30 proteins that play a vital role in the protection against various pathogens and diseases …
30 proteins that play a vital role in the protection against various pathogens and diseases …
Innate and adaptive immune responses against Influenza A Virus: Immune evasion and vaccination strategies
Influenza A virus (IAV) is a contagious respiratory infection causing pathogen responsible for
high morbidity and mortality rates across the planet. The human immune system contains a …
high morbidity and mortality rates across the planet. The human immune system contains a …
Targeting the tissue-complosome for curbing inflammatory disease
K Dutta, J Friscic, MH Hoffmann - Seminars in Immunology, 2022 - Elsevier
Hyperactivated local tissue is a cardinal feature of immune-mediated inflammatory diseases
of various organs such as the joints, the gut, the skin, or the lungs. Tissue-resident structural …
of various organs such as the joints, the gut, the skin, or the lungs. Tissue-resident structural …
Mechanistic understanding of lung inflammation: recent advances and emerging techniques
C Keskinidou, AG Vassiliou, I Dimopoulou… - Journal of …, 2022 - Taylor & Francis
Acute respiratory distress syndrome (ARDS) is a life-threatening lung injury characterized by
an acute inflammatory response in the lung parenchyma. Hence, it is considered as the most …
an acute inflammatory response in the lung parenchyma. Hence, it is considered as the most …
Identification of nifurtimox and chrysin as anti-influenza virus agents by clinical transcriptome signature reversion
Y Xin, S Chen, K Tang, Y Wu, Y Guo - International Journal of Molecular …, 2022 - mdpi.com
The rapid development in the field of transcriptomics provides remarkable biomedical
insights for drug discovery. In this study, a transcriptome signature reversal approach was …
insights for drug discovery. In this study, a transcriptome signature reversal approach was …
Targeting C5aR1 signaling reduced neutrophil extracellular traps and ameliorates COVID-19 pathology
Patients with severe COVID-19 develop acute respiratory distress syndrome (ARDS) that
may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that …
may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that …
O papel da sinalização do eixo C5a/C5aR1 na fisiopatologia COVID-19
BMS Silva - 2022 - teses.usp.br
Os doentes com COVID-19 grave desenvolvem a síndrome do desconforto respiratório
agudo (SDRA) que pode progredir para a tempestade de citocinas, disfunção de órgãos …
agudo (SDRA) que pode progredir para a tempestade de citocinas, disfunção de órgãos …