Chemical and enzymatic methods for post-translational protein–protein conjugation
RJ Taylor, MB Geeson, T Journeaux… - Journal of the …, 2022 - ACS Publications
Fusion proteins play an essential role in the biosciences but suffer from several key
limitations, including the requirement for N-to-C terminal ligation, incompatibility of …
limitations, including the requirement for N-to-C terminal ligation, incompatibility of …
T‐cell surface generation of dual bivalent, bispecific T‐cell engaging, RNA duplex cross‐linked antibodies (dbBiTERs) for re‐directed tumor cell lysis
M Kujawski, L Li, H Li, PJ Yazaki… - Biotechnology …, 2022 - Wiley Online Library
Abstract Background Genetic engineered Bispecific T‐cell engagers (BiTEs) generate
potent cytotoxic effects. Methods Alternately, click chemistry engineered, dual specific …
potent cytotoxic effects. Methods Alternately, click chemistry engineered, dual specific …
[PDF][PDF] Functional activity of CARCIK-CD19 cells compared to unmodified CIK cells combined with bispecific antibody blinatumomab
S Zaninelli, S Panna, I Cattaneo, C Cuofano… - … of innovative CAR … - boa.unimib.it
Abstract Although cytokine Induced Killer (CIK) cells have shown anti-tumor activity in vitro
and in vivo, there remains a need to increase their efficacy and specificity. This could be …
and in vivo, there remains a need to increase their efficacy and specificity. This could be …
Methods for assaying t-cell dependent bispecific antibodies
HY Lee, G Jiang, PY Wong, K Carey - US Patent 11,513,127, 2022 - Google Patents
The present invention provides a cell-based assay for mea suring T cell activation mediated
by a T cell-dependent bispecific antibody (TDB). In some aspects, the assay is useful for …
by a T cell-dependent bispecific antibody (TDB). In some aspects, the assay is useful for …
Dual bispecific antibody compounds and uses thereof
JE Shively, M Kujawski, L Li… - US Patent App. 17/632,869, 2022 - Google Patents
US20220280568A1 - Dual bispecific antibody compounds and uses thereof - Google Patents
US20220280568A1 - Dual bispecific antibody compounds and uses thereof - Google Patents …
US20220280568A1 - Dual bispecific antibody compounds and uses thereof - Google Patents …
Complementary rna linked bispecific t-cell engaging antibodies
JE Shively, L Li, M Kujawski… - US Patent App. 17 …, 2022 - Google Patents
US20220119552A1 - Complementary rna linked bispecific t-cell engaging antibodies - Google
Patents US20220119552A1 - Complementary rna linked bispecific t-cell engaging antibodies …
Patents US20220119552A1 - Complementary rna linked bispecific t-cell engaging antibodies …