Berberine as a natural modulator of inflammatory signaling pathways in the immune system: Focus on NF‐κB, JAK/STAT, and MAPK signaling pathways
SM Haftcheshmeh, M Abedi… - Phytotherapy …, 2022 - Wiley Online Library
Three main inflammatory signaling pathways include nuclear factor‐κB (NF‐κB), Janus
kinases/Signal transducer and activator of transcriptions (JAKs/STATs), and mitogen …
kinases/Signal transducer and activator of transcriptions (JAKs/STATs), and mitogen …
Central and peripheral regulations mediated by short-chain fatty acids on energy homeostasis
The human gut microbiota influences obesity, insulin resistance, and the subsequent
development of type 2 diabetes (T2D). The gut microbiota digests and ferments nutrients …
development of type 2 diabetes (T2D). The gut microbiota digests and ferments nutrients …
Corticosteroid resistance in asthma: Cellular and molecular mechanisms
G Caramori, F Nucera, S Mumby, FL Bello… - Molecular aspects of …, 2022 - Elsevier
Inhaled glucocorticoids (GCs) are drugs widely used as treatment for asthma patients. They
prevent the recruitment and activation of lung immune and inflammatory cells and …
prevent the recruitment and activation of lung immune and inflammatory cells and …
[HTML][HTML] Noncoding RNA-mediated macrophage and cancer cell crosstalk in hepatocellular carcinoma
Z Zhou, Z Wang, J Gao, Z Lin, Y Wang, P Shan… - Molecular Therapy …, 2022 - cell.com
The tumor microenvironment (TME) is a well-recognized system that plays an essential role
in tumor initiation, development, and progression. Intense intercellular communication …
in tumor initiation, development, and progression. Intense intercellular communication …
Design, Synthesis, and biological evaluation of HDAC6 inhibitors based on Cap modification strategy
X Li, X Liu, S Wang, X Shi, M Lu, X Hao, Y Fu… - Bioorganic …, 2022 - Elsevier
The abnormal biological functions of HDAC6 were closely related to the occurrence and
development of various tumors, making HDAC6 gradually become promising therapeutic …
development of various tumors, making HDAC6 gradually become promising therapeutic …
A New Gene Therapy for Pancreatic Cancer: STAT6-CYBB Decoy Oligodeoxynucleotides Focusing on Inhibiting M2 Macrophages
CJ Chen, HC Wang, YC Hou, YY Wu, CC Shieh… - 2022 - researchsquare.com
Background: M2 tumor-associated macrophages can promote pancreatic cancer
progression. Under ROS, cancer cells derived IL-4 can skew M2 with uncertain mechanism …
progression. Under ROS, cancer cells derived IL-4 can skew M2 with uncertain mechanism …