Genetics of ovarian insufficiency and defects of folliculogenesis

MM França, BB Mendonca - … practice & research Clinical endocrinology & …, 2022 - Elsevier
Primary ovarian insufficiency (POI) is determined by exhaustion of follicles in the ovaries,
which leads to infertility before the age of 40 years. It is characterized by a strong familial …

Artificial oocyte: development and potential application

RK Oqani, S So, Y Lee, JJ Ko, E Kang - Cells, 2022 - mdpi.com
Millions of people around the world suffer from infertility, with the number of infertile couples
and individuals increasing every year. Assisted reproductive technologies (ART) have been …

Novel bone morphogenetic protein 15 (BMP15) gene variants implicated in premature ovarian insufficiency

F Afkhami, S Shahbazi, L Farzadi, S Danaei - Reproductive Biology and …, 2022 - Springer
Background Bone morphogenetic protein 15 (BMP15) is expressed in oocytes and plays a
crucial role in the reproduction of mono-ovulating species. In humans, BMP15 gene …

Genome-wide identification, characterization and expression analysis of the BMP family associated with beak-like teeth in Oplegnathus

Y Ma, Y Xiao, Z Xiao, Y Wu, H Zhao, G Gao, L Wu… - Frontiers in …, 2022 - frontiersin.org
Bone morphogenetic proteins (BMPs), which belong to the transforming growth factor beta
(TGF-β) family, are critical for the control of developmental processes such as dorsal-ventral …

[HTML][HTML] Long-term changes in ovarian follicles of gilts exposed neonatally to methoxychlor: effects on oocyte-derived factors, anti-Müllerian hormone, follicle …

P Witek, M Grzesiak, M Koziorowski… - International Journal of …, 2022 - mdpi.com
In this paper, we investigated the effects of neonatal exposure to methoxychlor (MXC), a
synthetic organochlorine used as an insecticide with estrogenic, antiestrogenic, and …

Homozygous missense variants in BMPR15 can result in primary ovarian insufficiency

LAM Demain, K Metcalfe, E Boetje, P Clayton… - Reproductive …, 2022 - Elsevier
Research question Does a genetic condition underlie the diagnosis of primary ovarian
insufficiency (POI) in a 13-year-old girl with primary amenorrhoea? Design A case report of a …