The considerable development of carrier-free nanodrugs has been achieved due to their
high drug-loading capability, simple preparation method, and offering “all-in-one” functional …

The last decade witnessed the great advances in the development of nanomedicines. As a
kind of attractive nanomedicine, carrier-free nanomedicines received extensive …

Nanotechnology in medical applications, especially in oncology as drug delivery systems,
has recently shown promising results. However, although these advances have been …

In the current global crisis of antibiotic resistance, delivery systems are emerging to combat
resistant bacteria in a more efficient manner. Despite the significant advances of antibiotic …

Background Currently nanomedicines are the focus of attention from researchers and
clinicians because of the successes of lipid-nanoparticles-based COVID-19 vaccines …

Ruthenium complex is an important compound group for antitumor drug research and
development. NAMI-A, KP1019, TLD1433 and other ruthenium complexes have entered …

The outcomes of monotherapy could not satisfy clinical cancer treatment owing to the
challenges of tumor heterogeneity, multi-drug resistance, tumor metastasis and relapse. In …

The eminence of nano-scale materials prevailed after the invention of high-resolution
microscopes. Nowadays, nanoparticles are predominantly found in every application …

Parkinson's disease (PD) significantly affects patients' quality of life and represents a high
economic burden for health systems. Given the lack of safe and effective treatments for PD …

Abstract Clinical development of 7-ethyl-10‑hydroxy-camptothecin (SN38), the active
metabolite of irinotecan (CPT-11), is hindered by its insolubility and poor stability. Another …