Advances in the prevention and treatment of obesity-driven effects in breast cancers

K Chen, J Zhang, NM Beeraka, C Tang… - Frontiers in …, 2022 - frontiersin.org
Obesity and associated chronic inflammation were shown to facilitate breast cancer (BC)
growth and metastasis. Leptin, adiponectin, estrogen, and several pro-inflammatory …

Linking physical activity to breast cancer via sex hormones, part 1: the effect of physical activity on sex steroid hormones

CTV Swain, AE Drummond, L Boing, RL Milne… - … Biomarkers & Prevention, 2022 - AACR
The effect of physical activity on breast cancer risk may be partly mediated by sex steroid
hormones. This review synthesized and appraised the evidence for an effect of physical …

[HTML][HTML] The crosstalk within the breast tumor microenvironment in type II diabetes: Implications for cancer disparities

CS Ennis, P Llevenes, Y Qiu, R Dries… - Frontiers in …, 2022 - frontiersin.org
Obesity-driven (type 2) diabetes (T2D), the most common metabolic disorder, both increases
the incidence of all molecular subtypes of breast cancer and decreases survival in …

[PDF][PDF] Unopposed estrogens: current and future perspectives.

MM Oliva, R Gambioli, G Forte, G Porcaro… - European Review for …, 2022 - researchgate.net
Estrogens and progestogens act on female reproductive tissues in opposite ways. As they
counteract each other actions, the correct balance between these two classes of hormones …

Obesity, body image dissatisfaction, and sexual dysfunction: A narrative review

SM McNabney - Sexes, 2022 - mdpi.com
With approximately two-thirds of the United States adult population classified as overweight
or obese, obesity remains a critical public health concern. Obesity not only contributes to …

[HTML][HTML] The role of adipokines in pancreatic cancer

Q Wang, H Wang, Y Ding, M Wan, M Xu - Frontiers in Oncology, 2022 - frontiersin.org
In modern society, inappropriate diets and other lifestyle habits have made obesity, a
chronic epidemic that affects more than half of the world, an increasingly prominent health …

[HTML][HTML] Expression and prognostic value of ratios of platelet lymphocyte, neutrophil lymphocyte and lymphocyte monocyte in breast cancer patients

D Song, X Li, X Zhang - American Journal of Translational …, 2022 - ncbi.nlm.nih.gov
Background: The ratios of systemic inflammatory cells, neutrophil lymphocyte (NLR), platelet
lymphocyte (PLR) and lymphocyte monocyte (LMR) can be used as prognostic indicators of …

The role of liver kinase B1 in tumor progression through regulation of lipid metabolism

J Geng, Y Zhang, Q Meng, H Yan, Y Wang - Clinical and Translational …, 2022 - Springer
The somatic mutation of liver kinase B1 (LKB1) has been implicated in various tumors, which
is reflected in the survival, proliferation, and metastasis of tumor cells. However, the …

[HTML][HTML] Артериальная гипертензия и рак молочной железы у женщин: механизмы коморбидности и лекарственной ятрогении

ТА Бродская, БИ Гельцер, ТС Саталкина… - Артериальная …, 2022 - cyberleninka.ru
Сочетание артериальной гипертензии (АГ) и рака молочной железы (РМЖ) является
одним из наиболее частых клинических вариантов коморбидности сердечно …

Macrophages upregulate estrogen receptor expression in the model of obesity-associated breast carcinoma

D Nahmias Blank, E Hermano, A Sonnenblick… - Cells, 2022 - mdpi.com
Breast cancer (BC) and obesity are two heterogeneous conditions with a tremendous impact
on health. BC is the most commonly diagnosed neoplasm and the leading cause of cancer …