Essential roles for RNA in shaping nuclear organization

SA Quinodoz, M Guttman - Cold Spring Harbor …, 2022 - cshperspectives.cshlp.org
It has long been proposed that nuclear RNAs might play an important role in organizing the
structure of the nucleus. Initial experiments performed more than 30 years ago found that …

HSF1-activated non-coding stress response: Satellite lncRNAs and beyond, an emerging story with a complex scenario

C Vourc'h, S Dufour, K Timcheva, D Seigneurin-Berny… - Genes, 2022 - mdpi.com
In eukaryotes, the heat shock response is orchestrated by a transcription factor named Heat
Shock Factor 1 (HSF1). HSF1 is mostly characterized for its role in activating the expression …

Inhibition of mitochondrial complex III or dihydroorotate dehydrogenase (DHODH) triggers formation of poly(A)+ RNA foci adjacent to nuclear speckles following …

S Miyake, S Masuda - RNA biology, 2022 - Taylor & Francis
Intracellular and intercellular signalling networks play an essential role in optimizing cellular
homoeostasis and are thought to be partly reflected in nuclear mRNA dynamics. However …