Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …

The accumulation of an excessive amount of body fat can cause type 2 diabetes, and the
risk of type 2 diabetes increases linearly with an increase in body mass index. Accordingly …

Obesity usually is accompanied by inflammation of fat tissue, with a prominent role of
visceral fat. Chronic inflammation in obese fat tissue is of a lower grade than acute immune …

The SARS-CoV-2 pandemic continues to rage around the world. At the same time, despite
strong public health measures and high vaccination rates in some countries, a post-COVID …

Adipose tissue is a complex dynamic organ with whole-body immunometabolic influence.
Much of the work into understanding the role of immune cells in adipose tissue has been in …

Obesity and type 2 diabetes mellitus (T2DM) are increasing in prevalence owing to
decreases in physical activity levels and a shift to diets that include addictive and/or high …

Metabolic disorders, such as obesity, type 2 diabetes mellitus, and nonalcoholic fatty liver
disease, are characterized by chronic low-grade tissue and systemic inflammation. During …

Abstract Purpose of Review To discuss evidence supporting the use of glucagon-like
peptide 1 receptor agonists (GLP-1RA) to treat obesity and their role as a cardioprotective …

The mechanisms promoting disturbed white adipocyte function in obesity remain largely
unclear. Herein, we integrate white adipose tissue (WAT) metabolomic and transcriptomic …

Lipedema may be considered a model for healthy expandability of subcutaneous adipose
tissue (SAT). This condition is characterized by the disproportional and symmetrical SAT …