[HTML][HTML] Signaling mechanisms and pharmacological modulators governing diverse aquaporin functions in human health and disease

K Wagner, L Unger, MM Salman, P Kitchen… - International Journal of …, 2022 - mdpi.com
The aquaporins (AQPs) are a family of small integral membrane proteins that facilitate the
bidirectional transport of water across biological membranes in response to osmotic …

[HTML][HTML] Lens aquaporins in health and disease: Location is everything!

KL Schey, RB Gletten, CVT O'Neale, Z Wang… - Frontiers in …, 2022 - frontiersin.org
Cataract and presbyopia are the leading cause of vision loss and impaired vision,
respectively, worldwide. Changes in lens biochemistry and physiology with age are …

Environmentally relevant concentrations of F–53B induce eye development disorders-mediated locomotor behavior in zebrafish larvae

L Wu, M Zeeshan, Y Dang, LY Liang, YC Gong, QQ Li… - Chemosphere, 2022 - Elsevier
The perfluorooctane sulfonate alternative, F–53B, induces multiple physiological defects but
whether it can disrupt eye development is unknown. We exposed zebrafish to F–53B at four …

Aquaporin ion conductance properties defined by membrane environment, protein structure, and cell physiology

SW Henderson, S Nourmohammadi, SA Ramesh… - Biophysical …, 2022 - Springer
Aquaporins (AQPs) are multifunctional transmembrane channel proteins permeable to water
and an expanding array of solutes. AQP-mediated ion channel activity was first observed …

[HTML][HTML] Beyond the channels: adhesion functions of aquaporin 0 and connexin 50 in lens development

Z Li, Y Quan, S Gu, JX Jiang - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Lens, an avascular organ involved in light transmission, contains an internal micro-
circulatory system coupling ions to fluid movement, thus providing nutrients to internal lens …

Aquaporin-5 expression, trafficking, and interacting partners in the bovine lens

RB Gletten - 2022 - search.proquest.com
Abstract Aquaporin-5 (AQP5) regulates osmotic balance and transparency of the ocular lens
through facilitated diffusion of water and represents an integral component of the lens …