[HTML][HTML] Nutritional deficiency in an intestine-on-a-chip recapitulates injury hallmarks associated with environmental enteric dysfunction
Environmental enteric dysfunction (EED)—a chronic inflammatory condition of the intestine—
is characterized by villus blunting, compromised intestinal barrier function and reduced …
is characterized by villus blunting, compromised intestinal barrier function and reduced …
[HTML][HTML] Metabolomic profiling of triple negative breast cancer cells suggests that valproic acid can enhance the anticancer effect of cisplatin
A Granit, K Mishra, D Barasch… - Frontiers in Cell and …, 2022 - frontiersin.org
Cisplatin is an effective chemotherapeutic agent for treating triple negative breast cancer
(TNBC). Nevertheless, cisplatin-resistance might develop during the course of treatment …
(TNBC). Nevertheless, cisplatin-resistance might develop during the course of treatment …
Gut microbes shape microglia and cognitive function during malnutrition
Fecal‐oral contamination promotes malnutrition pathology. Lasting consequences of early
life malnutrition include cognitive impairment, but the underlying pathology and influence of …
life malnutrition include cognitive impairment, but the underlying pathology and influence of …
[HTML][HTML] Enhancement of fatty acid degradation pathway promoted glucoamylase synthesis in Aspergillus niger
J Qi, X Xiao, L Ouyang, C Yang, Y Zhuang… - Microbial Cell …, 2022 - Springer
Background Our recent multi-omics analyses of glucoamylase biosynthesis in Aspergillus
niger (A. niger) suggested that lipid catabolism was significantly up-regulated during high …
niger (A. niger) suggested that lipid catabolism was significantly up-regulated during high …
Mapping the influence of the gut microbiota on small molecules across the microbiome gut brain axis
H Hulme, LM Meikle, N Strittmatter… - Journal of the …, 2022 - ACS Publications
Microbes exert influence across the microbiome–gut–brain axis through neurotransmitter
production, induction of host immunomodulators, or the release or induction of other …
production, induction of host immunomodulators, or the release or induction of other …
[HTML][HTML] Plasma metabolic and lipidomic fingerprinting of individuals with increased intestinal permeability
The dual-sugar intestinal permeability test is a commonly used test to assess changes in gut
barrier function. However, it does not identify functional changes and the exact mechanism …
barrier function. However, it does not identify functional changes and the exact mechanism …
[HTML][HTML] The synergistic interaction of systemic inflammation, dysbiosis and antimicrobial resistance promotes growth restriction in children with acute severe …
R Arredondo-Hernandez, C Siebe… - Frontiers in …, 2022 - frontiersin.org
A healthy development is denied to millions of children worldwide as harsh life conditions
manifest themselves in an altered inflammation-prone microbiome crosstalk environment …
manifest themselves in an altered inflammation-prone microbiome crosstalk environment …
[HTML][HTML] Role of L-Carnitine supplementation on rate of weight gain and biomarkers of Environmental Enteric Dysfunction in children with severe acute malnutrition: A …
Background Severe acute malnutrition (SAM) and environmental enteric dysfunction (EED)
are highly prevalent among children residing in resource-limited countries like Bangladesh …
are highly prevalent among children residing in resource-limited countries like Bangladesh …
Multiomic analysis reveals microbiome-related relationships between cocaine use and metabolites
SS Martinez, V Stebliankin, J Hernandez, H Martin… - AIDS, 2022 - journals.lww.com
Objective: Over 19 million individuals globally have a cocaine use disorder, a significant
public health crisis. Cocaine has also been associated with a pro-inflammatory state and …
public health crisis. Cocaine has also been associated with a pro-inflammatory state and …
[PDF][PDF] Priority areas for reducing stunting in South Africa: Examining the implications of recent international evidence
This working paper summarises and discusses the most recent and best available
international evidence on stunting. Our aim is to inform and guide the public debate, the …
international evidence on stunting. Our aim is to inform and guide the public debate, the …