The aqueous solubility of active drug moiety plays a crucial role in the development of an
efficacious formulation. The poor aqueous solubility of BCS class II and IV drugs is …

The poor solubility of the antidiabetic drug gliclazide (Glc) is due to its hydrophobic nature.
This research is aimed at improving Glc's solubility and drug release profile, as well as at …

The solubility of glimepiride (GM) was improved from 1.6 μg/mL to 22.0 mg/mL when GM
and meglumine (MU) complexes were prepared. Therefore, transdermal hydrogels of GM …

Diabetes is defined by the World Health Organization (WHO) as a fasting plasma glucose
level above or equal to 126 mgdLÀ1 (or 7.0 mmolLÀ1) or plasma glucose above or equal to …

Cefuroxime axetil (CA) is BCS class II drug and has 55% absolute oral bioavailability due to
poor aqueous solubility hence the present work is an attempt to enhance the solubility and …

The reasons for the increasing consumer acceptance of these dosage forms are attributed to
their ability to overcome several of the drawbacks of tablet and capsule based products …

目的研究机械球磨法制备的吲哚美辛(Indometacin, IMC) 包合物对其溶解度及溶出度的影响.
方法采用机械球磨法制备IMC/羟丙基 β 环糊精(HP β CD) 和IMC/阿拉伯半乳聚糖(AG) …

Glimepiride (GM) is third generation sulfonylurea group and preferably used for the
treatment of type-II diabetes mellitus. It belongs to BCS class II drugs according to …

The pancreas, which is located deep in the abdomen, is a small organ, weighing around
100 g. However, its impact on the metabolism of the human body is significant. Despite the …

Glimepiride is an oral blood glucose lowering drug of sulfonylurea. Used as an adjunct to
diet and exercise to lower the blood glucose in patient with Type 2 diabetes mellitus …