The main limitation to the success of central nervous system (CNS) therapies lies in the
difficulty for drugs to cross the blood–brain barrier (BBB) and reach the brain. Regarding its …

Enteral administration is the most convenient route despite the gastrointestinal physiological
barriers. Nanostructured lipid carriers (NLCs) have emerged as a promising strategy for …

Background In recent years, the field of nanotechnology and nanomedicine has transformed
the pharmaceutical industry with the development of novel drug delivery systems that …

The potential for utilizing plant-derived components, such as plant proteins,
polysaccharides, lipids, and phospholipids, to create targeted drug delivery systems has …

The lipid-based colloidal carriers, such as nanostructured lipid carriers (NLCs), solid lipid
nanoparticles (SLNs), nanocapsules, liposomes, and microemulsion, are the latest and …

Apixaban (Apx), an oral anticoagulant drug, is a direct factor Xa inhibitor for the prophylaxis
against venous thromboembolism. Apx has limited oral bioavailability and poor water …

Breast cancer is the neoplasia of highest incidence in women worldwide. Docetaxel (DTX), a
taxoid used to treat breast cancer, is a BCS-class-IV compound (low oral bioavailability …

Advances in nanotechnology have generated a broad range of nanoparticles (NPs) for
numerous biomedical applications. Among the various properties of NPs are functionalities …

The purpose of the current study was to explore the suitability of nanostructured lipid carriers
(NLCs) loaded with a model drug calycosin for the treatment of breast cancer. NLCs were …

Delivery of anti-cancer agents is challenging due to some inherent problems associated with
them like instability, low solubility, non-specificity, variable pharmacokinetics, narrow …