Cuprotosis‐Related Genes: Predicting Prognosis and Immunotherapy Sensitivity in Pancreatic Cancer Patients

Y Xu, H Li, A Lan, Q Wu, Z Tang, D Shu… - Journal of …, 2022 - Wiley Online Library
Based on TCGA, GTEx, and TIMER databases and various bioinformatics analysis methods,
the potential biological roles of cuprotosis‐related genes in pancreatic cancer were deeply …

P16 gene promoter methylation is associated with oncogenesis and progression of gastric carcinomas: A systematic review and meta-analysis

LW Spagnol, J Polettini, DA Silveira… - Critical Reviews in …, 2022 - Elsevier
Introduction Gastric cancer is the fourth leading cause of neoplastic morbidity worldwide,
and its pathogenesis has been related to genetic and epigenetic alterations in cell cycle …

NFκB (RelA) mediates transactivation of hnRNPD in oral cancer cells

V Kumar, A Kumar, M Kumar, MR Lone, D Mishra… - Scientific Reports, 2022 - nature.com
Abstract Heterogeneous Ribonucleoprotein D (hnRNPD) is an RNA binding protein involved
in post-transcriptional regulation of multiple mediators of carcinogenesis. We previously …

Current insights into cellular senescence and myotoxicity induced by doxorubicin: The role of exercise and growth factors

C Andreou, A Matsakas - International Journal of Sports …, 2022 - thieme-connect.com
Doxorubicin is an anti-neoplasmic drug that prevents DNA replication but induces
senescence and cellular toxicity. Intensive research has focused on strategies to alleviate …

Depicting the role of CDKN2A in pancreatic differentiation exploiting a patient-specific human induced pluripotent stem cell model

M Schmid - 2022 - oparu.uni-ulm.de
In this study, hiPSCs derived from two patients carrying a heterozygous CDKN2A mutation
were differentiation towards the pancreatic lineage. The investigated CDKN2A mutation is …

Papel da metilação do Gene P16 na oncogênese e progressão de carcinomas gástricos: revisão sistemática

LW Spagnol - 2022 - rd.uffs.edu.br
Introdução: O câncer gástrico é a quarta principal causa de morbidade neoplásica no
mundo, e sua patogênese tem sido relacionada a alterações genéticas e epigenéticas em …