Mitochondria are highly dynamic organelles that participate in ATP generation and involve
calcium homeostasis, oxidative stress response, and apoptosis. Dysfunctional or damaged …

Atherosclerotic vascular disease and its complications are among the top causes of mortality
worldwide. In the vascular lumen, atherosclerotic plaques are not randomly distributed …

Vascular endothelial cells (VECs), which are lined up in the inner surface of blood vessels,
are in direct contact with the metabolite-related endogenous danger signals in the …

Objectives Melatonin has been reported to be an appropriate candidate for mitigating
various cardiovascular injuries, owing to its versatility. This study aimed to explore the role of …

Atherosclerosis—a systemic inflammatory disease—is the number one cause of mortality
and morbidity worldwide. As such, the prevention of disease progression is of global interest …

Hyperhomocysteinemia is an independent risk factor for atherosclerosis. It is known that
macrophage autophagy plays a protective role in atherosclerosis and that …

Background Oxidized low-density lipoproteins (ox-LDL) may induce foam cell formation from
the vascular smooth muscle cell (VSMC) by inhibiting VSMC autophagy. This process …

Atherosclerosis (AS) is a chronic inflammatory disease with the formation and accumulation
of macrophage‐derived foam cells in the subendothelial space of blood vessels as one …

Plumbagin (PLB) has been previously reported to alleviate myocardial ischemia/reperfusion
injury in vivo. In the present study, the potential of plumbagin to protect against hydrogen …

Atherosclerosis (AS) is one of the most common cardiovascular diseases and is the leading
cause of arteriosclerotic cardiovascular disease. Bile acids are not only the products of …