Osteoarthritis (OA) has maintained a prevalent public health problem worldwide over the
past decades. It is a global challenge because the specific pathogenesis of OA is unclear …

Progressive structural changes in osteoarthritis (OA) involve synovial inflammation and
angiogenesis, as well as activation of the proinflammatory cytokines tumor necrosis factor …

Objective Both obesity and synovitis are independently associated with knee osteoarthritis
(KOA) progression. We examined whether synovitis mediates the relationship between body …

Background: Heterogeneous phenotypes that display distinct common characteristics of
osteoarthritis (OA) are not well defined and will be helpful in identifying more customized …

Purpose Synovial inflammation in knee osteoarthritis (OA) causes disorganized synovial
angiogenesis and complement activation in synovial fluid, but links between complement …

The objective of this work was to assess the consequences of repeated intra-articular
injection of monosodium urate (MSU) crystals with inflammasome priming by …

Inflammation‐predominant osteoarthritis is an important clinical type of osteoarthritis, with
synovitis suggested as its distinct pathophysiology. We investigated whether the synovium's …

Osteoarthritis (OA) is a common type of arthritis, affecting millions of people around the
world. Angiopoietin-2 (Angpt-2) has a role in the development of chronic inflammatory …

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There is increasing evidence that osteoarthritis (OA) is caused by an active process of
inflammation and degeneration, rather than a passive age-related process of wear and tear …