Tumor associated macrophage and microbe: The potential targets of tumor vaccine delivery

J Jiang, J Mei, S Yi, C Feng, Y Ma, Y Liu, Y Liu… - Advanced drug delivery …, 2022 - Elsevier
The occurrence and development of tumors depend on the tumor microenvironment (TME),
which is made of various immune cells, activated fibroblasts, basement membrane …

[HTML][HTML] Liposomes as multifunctional nano-carriers for medicinal natural products

X Cheng, H Yan, S Pang, M Ya, F Qiu, P Qin… - Frontiers in …, 2022 - frontiersin.org
Although medicinal natural products and their derivatives have shown promising effects in
disease therapies, they usually suffer the drawbacks in low solubility and stability in the …

[HTML][HTML] Radiotherapy-induced remodeling of the tumor microenvironment by stromal cells

TJ Berg, A Pietras - Seminars in Cancer Biology, 2022 - Elsevier
Cancer cells reside amongst a complex milieu of stromal cells and structural features known
as the tumor microenvironment. Often cancer cells divert and co-opt functions of stromal …

[HTML][HTML] Targeting ferroptosis pathway to combat therapy resistance and metastasis of cancer

X Liu, Y Zhang, X Wu, F Xu, H Ma, M Wu… - Frontiers in …, 2022 - frontiersin.org
Ferroptosis is an iron-dependent regulated form of cell death caused by excessive lipid
peroxidation. This form of cell death differed from known forms of cell death in morphological …

Radiotherapy resistance: identifying universal biomarkers for various human cancers

I Larionova, M Rakina, E Ivanyuk, Y Trushchuk… - Journal of Cancer …, 2022 - Springer
Radiotherapy (RT) is considered as a standard in the treatment of most solid cancers,
including glioblastoma, lung, breast, rectal, prostate, colorectal, cervical, esophageal, and …

[HTML][HTML] Targeting replication stress response pathways to enhance genotoxic chemo-and radiotherapy

JA Nickoloff - Molecules, 2022 - mdpi.com
Proliferating cells regularly experience replication stress caused by spontaneous DNA
damage that results from endogenous reactive oxygen species (ROS), DNA sequences that …

[HTML][HTML] Intelligent design of polymer nanogels for full-process sensitized radiotherapy and dual-mode computed tomography/magnetic resonance imaging of tumors

C Zhang, W Tu, X Chen, B Xu, X Li, C Hu, M Shen… - Theranostics, 2022 - ncbi.nlm.nih.gov
Rationale: Development of intelligent radiosensitization nanoplatforms for imaging-guided
tumor radiotherapy (RT) remains challenging. We report here the construction of an …

Integrated molecular analysis reveals 2 distinct subtypes of pure seminoma of the testis

KE Medvedev, AV Savelyeva, KS Chen… - Cancer …, 2022 - journals.sagepub.com
Objective: Testicular germ cell tumors (TGCT) are the most common solid malignancy in
adolescent and young men, with a rising incidence over the past 20 years. Overall, TGCTs …

Prognostic impact of immune inflammation biomarkers in predicting survival and radiosensitivity in patients with non‐small‐cell lung cancer treated with …

E Delikgoz Soykut, Y Kemal, C Karacin… - Journal of medical …, 2022 - Wiley Online Library
Introduction The purpose of this retrospective study was to investigate the prognostic impact
of neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte ratio (PLR), derived NLR …

[HTML][HTML] Identifying key mutations of radioresponsive genes in esophageal squamous cell carcinoma

X Xu, Y Wang, Y Bai, J Lu, Y Guo, X Wang… - Frontiers in …, 2022 - frontiersin.org
Background Radiotherapy plays an important effect on the standard therapy of esophageal
squamous cell carcinoma (ESCC). However, the efficacy of the therapy is limited and a few …