Summary World Health Organization defines obesity as abnormal or excess adipose tissue
accumulation. Nowadays, this condition is a serious threat to the public health in most …

Obesity is a multifactorial and complex disease that often manifests in early childhood with a
lifelong burden. Polygenic and monogenic obesity are driven by the interaction between …

Based on the genetic contribution, childhood obesity can be classified into 3 groups:
common polygenic obesity, syndromic obesity, and monogenic obesity. More genetic …

Breast milk is the optimal food for infants and toddlers, providing basic nutrients. It is also a
source of many biologically active substances. Among them are hormones responsible for …

The improvement in childhood cancer treatments resulted in a marked improvement in the
survival of pediatric cancer patients. However, as survival increased, it was also possible to …

Résumé Face à l'augmentation de la prévalence de l'obésité et ses conséquences en
termes de santé publique, il est nécessaire de toujours mieux en comprendre la …

Breast milk contains adipokines such as resistin and leptin and is known for its protective
effect against obesity and insulin resistance. This pilot study aims to evaluate the correlation …

Monogenic obesity is a rare, early-onset, and severe form of obesity that has a Mendelian
inheritance pattern, high penetrance, and large genetic effect. In contrast, common …

Die Ätiologie der Adipositas ist multifaktoriell. Soziale Umweltfaktoren, wie Werbung oder
Konsumdruck, und stoffliche Umweltfaktoren, wie Fortbewegungsmittel, Architektur und die …

为解决重组人瘦素蛋白(hLeptin) 大规模生产过程中包涵体的形成以及体外重折叠过程中蛋白
聚集导致的低产量, 探究在大肠杆菌中hLeptin 高水平可溶性的表达, 并进行生物学活性检测 …