Early Th2 inflammation in the upper respiratory mucosa as a predictor of severe COVID-19 and modulation by early treatment with inhaled corticosteroids: a …

JR Baker, M Mahdi, DV Nicolau… - The Lancet …, 2022 - thelancet.com
Background Community-based clinical trials of the inhaled corticosteroid budesonide in
early COVID-19 have shown improved patient outcomes. We aimed to understand the …

[HTML][HTML] IL-36 receptor agonist and antagonist imbalance drives neutrophilic inflammation in COPD

JR Baker, PS Fenwick, CK Koss, HB Owles, SL Elkin… - JCI insight, 2022 - ncbi.nlm.nih.gov
Current treatments fail to modify the underlying pathophysiology and disease progression of
chronic obstructive pulmonary disease (COPD), necessitating alternative therapies. Here …

Prevalence of SARS-CoV-2 and co-infection with malaria during the first wave of the pandemic (the Burkina Faso case)

D López-Farfán, RS Yerbanga… - Frontiers in public …, 2022 - frontiersin.org
Africa accounts for 1.5% of the global coronavirus disease 2019 (COVID-19) cases and
2.7% of deaths, but this low incidence has been partly attributed to the limited testing …

Differential symptoms among COVID-19 outpatients before and during periods of SARS-CoV-2 Omicron variant dominance in Blantyre, Malawi: a prospective …

MG Chibwana, HW Thole, C Anscombe, PM Ashton… - MedRxiv, 2022 - medrxiv.org
Background It is widely reported that the SARS-CoV-2 Omicron variant has resulted in high
number of cases, but relatively low incidence of severe disease and deaths, compared to the …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Africa: current considerations and future projections

OT Idoko, E Usuf, U Okomo, C Wonodi… - Clinical Infectious …, 2022 - academic.oup.com
The burden of severe Covid-19 has been relatively low in sib-Saharan Africa compared to
Europe and the Americas. However, SARS-CoV-2 sero-prevalence data has demonstrated …

[HTML][HTML] Clinical Characteristics and Treatment Outcomes of COVID-19 Patients at Eka Kotebe General Hospital, Addis Ababa, Ethiopia

DK Huluka, EK Etissa, S Ahmed, HA Abule… - The American Journal …, 2022 - ncbi.nlm.nih.gov
Data from much of Africa are still scarce on the clinical characteristics, outcomes of
treatment, and factors associated with disease severity and mortality of COVID-19. A cross …

[PDF][PDF] Genomically informed clinical comparison of three epidemic waves of COVID-19 in Malawi

C Anscombe, S Lissauer, H Thole, J Rylance, D Dula… - medRxiv, 2022 - researchgate.net
Genomically informed clinical comparison of three epidemic waves of COVID-19 in Malawi
Page 1 1 Genomically informed clinical comparison of three epidemic waves of COVID-19 in …

Prevalence of SARS-CoV-2 and co-occurrence/co-infection with malaria during the first wave of the pandemic (the Burkina Faso case)

D López-Farfán, RS Yerbanga, M Parres-Mercader… - medRxiv, 2022 - medrxiv.org
Abstract Africa accounts for 1.5% of the global coronavirus disease 2019 (COVID-19) cases
and 2.7% of deaths, but this low incidence has been partly attributed to the limited testing …

Frequent shedding of multi-drug resistant pneumococci among adults living with HIV on suppressive antiretroviral therapy in Malawi

L Sibale, J Phiri, N Mitole, N Kalata, T Nyazika… - medRxiv, 2022 - medrxiv.org
People living with human immunodeficiency virus (PLHIV) on antiretroviral therapy (ART)
are reported to have three times higher carriage of Streptococcus pneumoniae than their …

Global Representation During a Global Pandemic

E Mlia-Phiri, S Lissauer, JE Weatherhead - JAMA pediatrics, 2022 - jamanetwork.com
The COVID-19 pandemic has highlighted the importance of international research
collaborations to quickly understand and successfully combat emerging and reemerging …