Klebsiella pneumoniae Biofilms and Their Role in Disease Pathogenesis

MES Guerra, G Destro, B Vieira, AS Lima… - Frontiers in cellular …, 2022 - frontiersin.org
The ability to form biofilms is a crucial virulence trait for several microorganisms, including
Klebsiella pneumoniae–a Gram-negative encapsulated bacterium often associated with …

Acute and chronic wound infections: microbiological, immunological, clinical and therapeutic distinctions

J Hurlow, PG Bowler - Journal of wound care, 2022 - magonlinelibrary.com
Wound infection is a complex pathology that may manifest either as a rapid onset acute
condition, or as a prolonged chronic condition. Although systemic antibiotic therapy is often …

Hyaluronic acid-based wound dressing with antimicrobial properties for wound healing application

F Della Sala, G Longobardo, A Fabozzi, M di Gennaro… - Applied Sciences, 2022 - mdpi.com
Wound healing is a naturally occurring process that can be aided by a wound dressing
properly designed to assure an efficient healing process. An infection caused by several …

Engineered nanotechnology: an effective therapeutic platform for the chronic cutaneous wound

S Mallick, M Nag, D Lahiri, S Pandit, T Sarkar, S Pati… - Nanomaterials, 2022 - mdpi.com
The healing of chronic wound infections, especially cutaneous wounds, involves a complex
cascade of events demanding mutual interaction between immunity and other natural host …

Biofilm-associated infections in chronic wounds and their management

JB Aswathanarayan, P Rao, S Hm, S Gs… - Advances in Microbiology …, 2022 - Springer
Chronic wounds including vascular ulcers, diabetic ulcers, pressure ulcers, and burn
wounds show delayed progress through the healing process. Some of their common …

Nanofibrous dressing: Potential alternative for fighting against antibiotic‐resistance wound infections

Y Zhang, J Yu, H Zhang, Y Li… - Journal of Applied …, 2022 - Wiley Online Library
The progression of antibiotic‐resistant bacteria (ARB) as well as impaired immunity due to
chronic diseases and complications, aging, and so forth pose opportunities in parallel with …

Recalcitrant Ulcerative Pyoderma Gangrenosum of the Leg Responsive to Tildrakizumab: A Case Report

LJ Leow, N Zubrzycki - Clinical, Cosmetic and Investigational …, 2022 - Taylor & Francis
Elevated levels of inflammatory mediators—including the interleukin IL-23—are implicated
in the pathogenesis of pyoderma gangrenosum (PG), an autoinflammatory neutrophilic …

Murine burn lesion model for studying acute and chronic wound infections

H Calum, H Trøstrup, AS Laulund, K Thomsen… - APMIS, 2022 - Wiley Online Library
Acute wounds, such as thermal injury, and chronic wounds are challenging for patients and
the healthcare system around the world. Thermal injury of considerable size induces …

[HTML][HTML] 动物模型在细菌生物被膜研究中的应用与展望

徐欢, 刘静, 张昭寰, 陶倩, 黄振华, 潘迎捷, 赵勇 - 生物工程学报, 2022 - cjb.ijournals.cn
细菌生物被膜的形成与其致病性, 耐药性密切相关, 在许多由细菌导致的慢性,
亚慢性感染中发挥着重要作用. 动物模型广泛应用于细菌生物被膜相关感染的研究中 …

An in vitro and ex vivo wound infection model to test topical and systemic treatment with antibiotics

Y Cheng, PA De Bank, A Bolhuis - Journal of Applied …, 2022 - academic.oup.com
Aims This study aimed to develop a wound infection model that could be used to test
antibiotic‐loaded electrospun matrices for the topical treatment of infected skin and compare …