The mitochondrial unfolded protein response (UPRmt): shielding against toxicity to mitochondria in cancer

JR Inigo, D Chandra - Journal of hematology & oncology, 2022 - Springer
Mitochondria are essential for tumor growth and progression. However, the heavy demand
for mitochondrial activity in cancer leads to increased production of mitochondrial reactive …

Spexin: Its role, regulation, and therapeutic potential in the hypothalamus

A Tran, W He, JTC Chen, DD Belsham - Pharmacology & therapeutics, 2022 - Elsevier
Spexin is the most recently discovered member of the galanin/kisspeptin/spexin family of
peptides. This 14-amino acid peptide is highly conserved and is implicated in homeostatic …

Investigation of the crosstalk between GRP78/PERK/ATF-4 signaling pathway and renal apoptosis induced by nephropathogenic infectious bronchitis virus infection

W Chen, C Huang, Y Shi, N Li, E Wang, R Hu… - Journal of …, 2022 - Am Soc Microbiol
This study aims to explore the crosstalk between GRP78/PERK/ATF-4 signaling pathway
and renal apoptosis induced by nephropathogenic infectious bronchitis virus (NIBV). Hy …

Role of lncRNA LIPE-AS1 in adipogenesis

A Thunen, D La Placa, Z Zhang, JE Shively - Adipocyte, 2022 - Taylor & Francis
Recent studies have identified long non-coding RNAs (lncRNAs) as potential regulators of
adipogenesis. In this study, we have characterized a lncRNA, LIPE-AS1, that spans genes …

FAdV-4 induce autophagy via the endoplasmic reticulum stress-related unfolded protein response

H Ma, Y Ding, K Du, K Chang, Y Niu - Veterinary Microbiology, 2022 - Elsevier
Hydropericardium syndrome caused by the fowl adenovirus serotype 4 (FAdV-4) is
prevalent disease in China with a high mortality rate. Many studies have demonstrated some …

Benzophenones alter autophagy and ER stress gene expression in pancreatic beta cells in vitro

F Szulak, L Etcheverry Boneo… - In Vitro Cellular & …, 2022 - Springer
Benzophenones (BPs) are endocrine disruptors frequently used in sunscreens and food
packaging as UV blockers. Our goal was to assess the effect of benzophenone 2 (BP2) and …