The bumpy road to stem cell therapies: Rational design of surface topographies to dictate stem cell mechanotransduction and fate

J Carthew, JBJ Taylor, MR Garcia-Cruz… - … Applied Materials & …, 2022 - ACS Publications
Cells sense and respond to a variety of physical cues from their surrounding
microenvironment, and these are interpreted through mechanotransductive processes to …

Recent innovations in surface topography

L Chambers, P Roach, N Shirtcliffe - Surface Innovations, 2022 - icevirtuallibrary.com
In this review, the authors provide a general review of current research themes where
complex surface topography plays a role. Recent innovations and research possibilities …

Regulation of mesenchymal stem cell morphology using hydrogel substrates with tunable topography and photoswitchable stiffness

SR Moxon, D Richards, O Dobre, LS Wong, J Swift… - Polymers, 2022 - mdpi.com
Cell function can be directly influenced by the mechanical and structural properties of the
extracellular environment. In particular, cell morphology and phenotype can be regulated via …

Regulatory effects of gradient microtopographies on synapse formation and neurite growth in hippocampal neurons

R McNaughton, Y Huo, G Li, ADV Ioschpe… - Journal of …, 2022 - iopscience.iop.org
Among approaches aiming toward functional nervous system restoration, those
implementing microfabrication techniques allow the manufacture of platforms with distinct …