Trypanosoma cruzi, the agent of Chagas disease (ChD), exhibits remarkable biological and
genetic diversity, along with eco-epidemiological complexity. In order to facilitate …

The complexity of host–pathogen interactions often leads to distinct clinical outcomes upon
infection with different pathogen strains. In this Review, we explore the interactions between …

Chagas disease (CD) is caused by the parasite Trypanosoma cruzi, and it is endemic in
Central, South America, Mexico and the South of the United States. It is an important cause …

There is no consensus on the diagnostic algorithms for many scenarios of Trypanosoma
cruzi infection, which hinders the establishment of governmental guidelines in endemic and …

Background Rhodnius prolixus is considered the most relevant Trypanosoma cruzi vector in
Colombia and Venezuela due it is responsible for domestic transmission in both countries …

The parasites are repeatedly confronting their host to take advantage of nutrients for
multiplication and survival. In this sense, a wide spectrum of molecules is released from both …

Canis lupus familiaris (domestic dog) represents a reliable sentinel for the occurrence of a
well-established transmission cycle of Trypanosoma cruzi among wild mammals in the …

The vast majority of trypanosome species is vector-borne parasites, with some of them being
medically and veterinary important (such as Trypanosoma cruzi and Trypanosoma brucei) …

BACKGROUND Trypanosoma cruzi shows an exuberant genetic diversity. Currently, seven
phylogenetic lineages, called discrete typing units (DTUs), are recognised: TcI-TcVI and …

Bats (the order Chiroptera) account for more than 20% of all mammalian species in the
world; remarkably, they are the only mammals capable of true and sustained flight using …