Bidirectional crosstalk along the gut-liver axis controls gastrointestinal health and disease
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …

Cancer cells acquire distinct metabolic preferences based on their tissue of origin, genetic
alterations and degree of interaction with systemic hormones and metabolites. These …

Time-restricted feeding (TRF) improves metabolic health. Both early TRF (eTRF, food intake
restricted to the early part of the day) and mid-day TRF (mTRF, food intake restricted to the …

In tumor-bearing mice, cyclic fasting or fasting-mimicking diets (FMD) enhance the activity of
antineoplastic treatments by modulating systemic metabolism and boosting antitumor …

Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Background & Aims Previous single-cell RNA-sequencing analyses have shown that Trem2-
expressing macrophages are present in the liver during obesity, non-alcoholic …

Adipose tissue is a complex dynamic organ with whole-body immunometabolic influence.
Much of the work into understanding the role of immune cells in adipose tissue has been in …

Nutrition affects all physiological processes including those linked to the development and
function of our immune system. Here, we discuss recent evidence and emerging concepts …

Cellular metabolism constitutes a fundamental process in biology. During tumor initiation
and progression, each cellular component in the cancerous niche undergoes dramatic …

Despite the popular use of dietary supplements during conventional cancer treatments, their
impacts on the efficacies of prevalent immunotherapies, including immune-checkpoint …