Global mapping of RNA G-quadruplexes (G4-RNAs) using G4RP-seq

SY Yang, D Monchaud, JMY Wong - Nature Protocols, 2022 - nature.com
Guanine-rich RNAs can fold into four-stranded structures, termed G-quadruplexes (G4-
RNAs), and participate in a wide range of biological processes. Here we describe in detail a …

Ruthenium (II) Polypyridyl Complexes and Their Use as Probes and Photoreactive Agents for G-quadruplexes Labelling

J Jiang, T Teunens, J Tisaun, L Denuit, C Moucheron - Molecules, 2022 - mdpi.com
Due to their optical and electrochemical properties, ruthenium (II) polypyridyl complexes
have been used in a wide array of applications. Since the discovery of the light-switch ON …

Gaining Insights on the Interactions of a Class of Decorated (2‐([2, 2′‐Bipyridin]‐6‐yl) phenyl) platinum Compounds with c‐Myc Oncogene Promoter G‐Quadruplex …

L Savva, M Fossépré, O Keramidas… - … A European Journal, 2022 - Wiley Online Library
Organometallic molecules offer some of the most promising scaffolds for interaction with G‐
quadruplex nucleic acids. We report the efficient synthesis of a family of organoplatinum (II) …

A novel fluorescent probe with a pyrazolo [4, 3-c] quinoline core selectively recognizes c-MYC promoter G-quadruplexes

HI Mohamed, C Gao, Z Gui, Z Song, D Wei - New Journal of Chemistry, 2022 - pubs.rsc.org
An aptamer combined with a fluorophore could work as the fluorescent core of nucleic acid
mimics of fluorescent proteins to locate and image functional biomolecules in cells. The …

Illuminating the G-Quadruplex: A Review on Fluorescent Probes for Detecting Polymorphic G-Quartet DNA Structures

SK Ganegamage, MD Heagy - Current Organic Chemistry, 2022 - ingentaconnect.com
Modulating crucial biological processes such as gene regulation, aging, and relationship to
globally important human health issues such as cancer has significantly brought …

Discovery of a fluorescent, long chain-bridged bispurine that selectively targets the c-MYC G-quadruplex

MH Hu, JH Lin, Q Huang - Bioorganic Chemistry, 2022 - Elsevier
Abstract G-quadruplexes (G4s) are special nucleic acid structures which are involved in the
regulation of some key biological events like transcription and translation, which are now …

[图书][B] Design, Synthesis, and Characterization of Mechanosensitive Dual Fluorescent Dyes as Potential Probes for Biological Applications

SK Ganegamage - 2022 - search.proquest.com
Design, Synthesis, and Characterization of Mechanosensitive Dual Fluorescent Dyes as
Potential Probes for Biological Applications Abstract Dual fluorescence is a rare optical …

Investigation Of Genomic Instability Induced By G-Quadruplexes In The Absence Of Functional Topoisomerase 1 In Yeast

A Berroyer - 2022 - digitalcommons.library.tmc.edu
Abstract Topoisomerase 1 (Top1) is an enzyme that removes transcriptionally generated
negative supercoils by binding and nicking DNA. Since transcription of guanine-rich DNA …

[PDF][PDF] Charakterisierung der Bindung humaner Proteine an G-Quadruplex-DNA und-RNA

SC Eiden - 2022 - publications.rwth-aachen.de
Den erwiesenermaßen höchsten Stabilisierungseffekt weist das Kaliumion (K+) auf, das
wegen seines Radius von 1, 33 Å zwischen zwei übereinanderliegenden G-Tetraden …