Emerging roles of inflammasomes in cardiovascular diseases

Y Liao, K Liu, L Zhu - Frontiers in Immunology, 2022 - frontiersin.org
Cardiovascular diseases are known as the leading cause of morbidity and mortality
worldwide. As an innate immune signaling complex, inflammasomes can be activated by …

[HTML][HTML] Exosomes in atherosclerosis: Convergence on macrophages

K Yang, Q Xiao, M Niu, X Pan, X Zhu - International Journal of …, 2022 - ncbi.nlm.nih.gov
As the primary cells of atherosclerotic plaques, macrophages play a central role in the
occurrence and progression of atherosclerosis (AS). In recent years, macrophages have …

[HTML][HTML] Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis

B Wang, X Tang, L Yao, Y Wang… - The Journal of …, 2022 - Am Soc Clin Investig
JCI - Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis Go
to JCI Insight About Editors Consulting Editors For authors Publication ethics Alerts Advertising …

[PDF][PDF] Bocs, an

PM Boarescu, I Boarescu, RM Pop, SH Rosian - Int. J. Mol. Sci, 2022 - academia.edu
The present study aims to compare the oxidative stress biomarkers, pro-inflammatory
cytokines, and histological changes induced by three cardiovascular risk factors, namely …

Evaluation of oxidative stress biomarkers, pro-inflammatory cytokines, and histological changes in experimental hypertension, dyslipidemia, and type 1 diabetes …

PM Boarescu, I Boarescu, RM Pop, ŞH Roşian… - International Journal of …, 2022 - mdpi.com
The present study aims to compare the oxidative stress biomarkers, pro-inflammatory
cytokines, and histological changes induced by three cardiovascular risk factors, namely …

Capsaicin Ameliorates High-Fat Diet-Induced Atherosclerosis in ApoE−/− Mice via Remodeling Gut Microbiota

Z Dai, S Li, Y Meng, Q Zhao, Y Zhang, Z Suonan, Y Sun… - Nutrients, 2022 - mdpi.com
Capsaicin is a pungent alkaloid abundantly present in peppers with outstanding biological
activities, including the anti-atherosclerosis effect. Previous studies revealed that gut …

Bioactive Peptides from Lupin (Lupinus angustifolius) Prevent the Early Stages of Atherosclerosis in Western Diet-Fed ApoE–/– Mice

G Santos-Sánchez, I Cruz-Chamorro… - Journal of agricultural …, 2022 - ACS Publications
We have previously reported the in vitro hypocholesterolemic, anti-inflammatory, and
antioxidant effects of Alcalase-generated lupin protein hydrolysate (LPH). Given that …

Therapeutic potential of stem cell-derived extracellular vesicles on atherosclerosis-induced vascular dysfunction and its key molecular players

IK Comariţa, A Vîlcu, A Constantin… - Frontiers in cell and …, 2022 - frontiersin.org
Atherosclerosis is a progressive, chronic inflammatory disease of the large arteries caused
by the constant accumulation of cholesterol, followed by endothelial dysfunction and …

Development and clinical translation of P2X7 receptor antagonists: A potential therapeutic target in coronary artery disease?

E Genetzakis, J Gilchrist, M Kassiou… - Pharmacology & …, 2022 - Elsevier
The purinoceptor 7 receptor (P2X 7 R) plays an important role in promoting inflammation in
response to accumulating damage-associated molecular patterns (DAMPs) released from …

Nanobiotechnology approaches for cardiovascular diseases: site-specific targeting of drugs and nanoparticles for atherothrombosis

H Liu, G Pietersz, K Peter, X Wang - Journal of Nanobiotechnology, 2022 - Springer
Atherosclerosis and atherothrombosis, the major contributors to cardiovascular diseases
(CVDs), represent the leading cause of death worldwide. Current pharmacological therapies …