SET8 inhibition potentiates radiotherapy by suppressing DNA damage repair in carcinomas

PAN Dong, YR Du, LI Rong, AH Shen, XD Liu… - Biomedical and …, 2022 - Elsevier
Objective SET8 is a member of the SET domain-containing family and the only known lysine
methyltransferase (KMT) that monomethylates lysine 20 of histone H4 (H4K20me1). SET8 …

Matrix Metalloproteinases in Colorectal Cancer

N Merchant, A Alam - Onco Therapeutics, 2022 - dl.begellhouse.com
Matrix metalloproteinases (MMPs) plays a significant role in tumor advancement and growth.
The extracellular matrix (ECM) destruction is controlled by MMPs that is considered as an …