It is particularly challenging to develop a truly effective pharmacotherapy for cocaine use
disorder (CUD) treatment. Accelerating cocaine metabolism via hydrolysis at cocaine …

Cocaine blocks dopamine uptake via dopamine transporter (DAT) on plasma membrane of
neuron cells and, as a result, produces the high and induces DAT trafficking to plasma …

As most cocaine users drink alcohol, it is interesting to understand how a non-lethal dose of
alcohol affects the metabolism and toxicity of cocaine. In this study, we examined the …

This chapter describes the specific clinical syndromes associated with drugs of abuse. Drug
abuse is associated with many medical problems and complications stemming both from …