Systemic sclerosis–associated interstitial lung disease: How to incorporate two food and drug administration–approved therapies in clinical practice

D Khanna, A Lescoat, D Roofeh… - Arthritis & …, 2022 - Wiley Online Library
Systemic sclerosis (SSc; scleroderma) has the highest individual mortality of all rheumatic
diseases, and interstitial lung disease (ILD) is among the leading causes of SSc‐related …

[HTML][HTML] Current advances in the treatment of systemic sclerosis

H Bukiri, ER Volkmann - Current opinion in pharmacology, 2022 - Elsevier
Systemic sclerosis (SSc) is a rare, systemic autoimmune disease of unknown etiology.
Among the systemic rheumatic diseases, SSc carries the highest mortality, in part due to the …

Lung function trajectory in progressive fibrosing interstitial lung disease

JM Oldham, CT Lee, Z Wu, WS Bowman… - European …, 2022 - Eur Respiratory Soc
Background Proposed criteria for progressive fibrosing interstitial lung disease (PF-ILD)
have been linked to increased mortality risk, but lung function trajectory after satisfying …

JAK inhibitors and systemic sclerosis: a systematic review of the literature

C Moriana, T Moulinet, R Jaussaud, P Decker - Autoimmunity reviews, 2022 - Elsevier
Abstract Background Systemic sclerosis (SSc) is a systemic autoimmune disease with
heterogeneous clinical presentation and prognosis. JAK inhibitors reduced cutaneous and …

Development of antifibrotic therapy for stricturing Crohn's disease: lessons from randomized trials in other fibrotic diseases

SN Lin, R Mao, C Qian, D Bettenworth… - Physiological …, 2022 - journals.physiology.org
Intestinal fibrosis is considered an inevitable complication of Crohn's disease (CD) that
results in symptoms of obstruction and stricture formation. Endoscopic or surgical treatment …

Immunomodulatory treatment of interstitial lung disease

L van den Bosch, F Luppi, G Ferrara… - … in Respiratory Disease, 2022 - journals.sagepub.com
Interstitial lung diseases (ILDs) other than idiopathic pulmonary fibrosis (IPF) have an array
of immunomodulatory treatment options compared with IPF, due to their inflammatory …

Advances in the management of idiopathic pulmonary fibrosis and progressive pulmonary fibrosis

GY Liu, GRS Budinger, JE Dematte - Bmj, 2022 - bmj.com
Similarly to idiopathic pulmonary fibrosis (IPF), other interstitial lung diseases can develop
progressive pulmonary fibrosis (PPF) characterized by declining lung function, a poor …

Systemic scleroderma—definition, clinical picture and laboratory diagnostics

A Kowalska-Kępczyńska - Journal of clinical medicine, 2022 - mdpi.com
(1) Background: Scleroderma (Sc) is a rare connective tissue disease classified as an
autoimmune disorder. The pathogenesis of this disease is not fully understood.(2) Methods …

Interstitial lung disease in rheumatoid arthritis: a practical review

A Laria, AM Lurati, G Zizzo, E Zaccara… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic inflammatory disease, which primarily causes
symmetric polyarthritis. An extrarticolar involvement is common, and the commonly involved …

New era in systemic sclerosis treatment: recently approved therapeutics

S Ebata, A Yoshizaki-Ogawa, S Sato… - Journal of Clinical …, 2022 - mdpi.com
Systemic sclerosis (SSc) is a chronic autoimmune disease with a poor prognosis. Among the
various complications of SSc, treatment options for the fibrotic lesions, skin sclerosis, and …