[HTML][HTML] A review on the role of TRP channels and their potential as drug targets_an insight into the TRP channel drug discovery methodologies
HP Fallah, E Ahuja, H Lin, J Qi, Q He, S Gao… - Frontiers in …, 2022 - frontiersin.org
Transient receptor potential (TRP) proteins are a large group of ion channels that control
many physiological functions in our body. These channels are considered potential …
many physiological functions in our body. These channels are considered potential …
Taste and smell: a unifying chemosensory theory
Since antiquity, the sense of smell (olfaction) is considered as a distance sense, just like
sight and hearing. Conversely, the sense of taste (gustation) is thought to operate by direct …
sight and hearing. Conversely, the sense of taste (gustation) is thought to operate by direct …
[HTML][HTML] Dietary Inflammatory Index (DII) is Associated with Movement-Evoked Pain Severity in Adults with Chronic Low Back Pain: Sociodemographic Differences.
Chronic low back pain (CLBP) is one of the leading causes of pain and disability in adults in
the United States and disproportionately burdens non-Hispanic Black (NHB) individuals and …
the United States and disproportionately burdens non-Hispanic Black (NHB) individuals and …
E-cigarette Flavors, Sensory Perception, and Evoked Responses
SK Alhadyan, V Sivaraman… - Chemical research in …, 2022 - ACS Publications
The chemosensory experiences evoked by flavors encompass a number of unique
sensations that include olfactory stimuli (smell), gustatory stimuli (taste, ie, salty, sweet, sour …
sensations that include olfactory stimuli (smell), gustatory stimuli (taste, ie, salty, sweet, sour …
[HTML][HTML] Dysmenorrhoea: Can Medicinal Cannabis Bring New Hope for a Collective Group of Women Suffering in Pain, Globally?
A Seifalian, J Kenyon, V Khullar - International Journal of Molecular …, 2022 - mdpi.com
Dysmenorrhoea effects up to 90% of women of reproductive age, with medical management
options including over-the-counter analgesia or hormonal contraception. There has been a …
options including over-the-counter analgesia or hormonal contraception. There has been a …
[HTML][HTML] Not only COVID-19: involvement of multiple chemosensory systems in human diseases
A Caretta, C Mucignat-Caretta - Frontiers in Neural Circuits, 2022 - frontiersin.org
Chemosensory systems are deemed marginal in human pathology. In appraising their role,
we aim at suggesting a paradigm shift based on the available clinical and experimental data …
we aim at suggesting a paradigm shift based on the available clinical and experimental data …
Localization of TRP channels in healthy oral mucosa from human donors
Y Moayedi, S Michlig, M Park, A Koch, EA Lumpkin - eneuro, 2022 - eneuro.org
The oral cavity is exposed to a remarkable range of noxious and innocuous conditions,
including temperature fluctuations, mechanical forces, inflammation, and environmental and …
including temperature fluctuations, mechanical forces, inflammation, and environmental and …
[HTML][HTML] Antagonism of the transient receptor potential melastatin‑2 channel leads to targeted antitumor effects in primary human malignant melanoma cells
SG McKamey, LR Jira, CM Tweed… - International …, 2022 - spandidos-publications.com
Melanoma continues to be the most aggressive and devastating form of skin cancer for
which the development of novel therapies is required. The present study aimed to determine …
which the development of novel therapies is required. The present study aimed to determine …
Anatomy, physiology, and neurobiology of olfaction, gustation, and chemesthesis
RB Jaime-Lara, L To, PV Joseph - Sensory science and chronic diseases …, 2022 - Springer
Olfaction and gustation allow us to monitor and adapt to our internal and external
environments, including our ability to choose foods and avoid potential hazards. Olfactory …
environments, including our ability to choose foods and avoid potential hazards. Olfactory …
[HTML][HTML] Mechanisms of Actions Involved in The Antinociceptive Effect of Estragole and its β-Cyclodextrin Inclusion Complex in Animal Models
RHS da Costa, AOBPB Martins, RT Pessoa… - Plants, 2022 - mdpi.com
(1) Background: estragole is a monoterpene found in the essential oils of several aromatic
plants, which can be used for several pharmacological activities. The aim of this study was to …
plants, which can be used for several pharmacological activities. The aim of this study was to …