As distinct cancer biomarkers have been discovered in recent years, a need to reclassify
tumors by more than their histology has been proposed, and therapies are now tailored to …

Muscle invasive bladder cancer (MIBC) is a widespread malignancy with a worse prognosis
often related to a late diagnosis. For early-stage MIBC pts, a multidisciplinary approach is …

Management of first-line advanced urothelial carcinoma (UC) has consisted during the past
three decades in the administration of platinum-based chemotherapy followed by …

Emerging clinical evidence indicates that the combination of local administration of
immunotherapy with systemic immune-checkpoint blockade targeting the PD-1/PD-L1 …

Objectives Although the preoperative assessment of whether a bladder cancer (BCa)
indicates muscular invasion is crucial for adequate treatment, there currently exist some …

Opinion statement As we come to better understand cancer genomics, we are increasingly
shifting towards precision medicine. FGFR has been elucidated as one of the oncogenic …

Deep learning (DL) is a rapidly developing field in machine learning (ML). The concept of
deep learning originates from research on artificial neural networks and is an upgrade of …

Patients with muscle-invasive urothelial carcinoma achieving pathological complete
response (pCR) upon neoadjuvant chemotherapy (NAC) have improved prognosis …

In recent years, with the breakthrough of CAR-T cells in the treatment of hematological
tumors, they are increasingly being used to treat solid tumors, including urologic neoplasms …

In bladder cancer patients, metastasis after surgical resection and serious adverse reactions
brought by cisplatin-based systemic chemotherapy make it urgent to explore novel …