Transcriptome Profiling of ADAR1 Targets in Triple-Negative Breast Cancer Cells Reveals Mechanisms for Regulating Growth and Invasion

AR Baker, C Miliotis, J Ramírez-Moya, T Marc… - Molecular Cancer …, 2022 - AACR
ADARs catalyze adenosine-to-inosine (A-to-I) editing of double-stranded RNA and regulate
global gene expression output through interactions with RNA and other proteins. ADARs …

The A-to-I editing of KPC1 promotes intrahepatic cholangiocarcinoma by attenuating proteasomal processing of NF-κB1 p105 to p50

C Gao, G Zhou, J Shi, P Shi, L Jin, Y Li, X Wang… - Journal of Experimental …, 2022 - Springer
Background Aberrant RNA editing of adenosine-to-inosine (A-to-I) has been linked to
multiple human cancers, but its role in intrahepatic cholangiocarcinoma (iCCA) remains …

Pterostilbene ameliorates the disrupted Adars expression and improves liver fibrosis in DEN-induced liver injury in Wistar rats: A novel potential effect

MI Mohamad, IA Desoky, KA Zaki, DR Sadek… - Gene, 2022 - Elsevier
The knowledge of RNA editing modifications and its subsequent proteomic diversity in is still
limited and represents only the tip of the iceberg. Adenosine to inosine (A-to-I) RNA editing …

A-to-I RNA editing of BLCAP promotes cell proliferation by losing the inhibitory of Rb1 in colorectal cancer

F Han, M Hu, L Zhang, X Fan, J Wang, Z Lou… - Experimental Cell …, 2022 - Elsevier
The bladder cancer-associated protein (BLCAP) gene is a tumor-suppressor gene as its
encoded protein can inhibit cell proliferation by stimulating apoptosis in many malignant …

Hepatocarcinogenesis and the role of next-generation sequencing in liver cancer

NB Stephen, D Madduru, P Pappu, U Vijay… - … and Precision Medicine …, 2022 - Elsevier
Liver cancer is the third most frequent cause of cancer deaths worldwide. The most common
form of primary liver cancer is hepatocellular carcinoma (HCC). The high mortality rate in …

ADAR1 and RNA editing in triple-negative breast cancer

AR Baker - 2022 - search.proquest.com
Abstract The family of Adenosine Deaminases Acting on RNA (ADARs) regulate global gene
expression output by catalyzing Adenosine-to-Inosine (A-to-I) editing of double-stranded …