Pancreatic cancer: pathogenesis, screening, diagnosis, and treatment
Pancreatic ductal adenocarcinoma (PDAC) is a clinically challenging cancer, due to both its
late stage at diagnosis and its resistance to chemotherapy. However, recent advances in our …
late stage at diagnosis and its resistance to chemotherapy. However, recent advances in our …
[HTML][HTML] Timeline of development of pancreatic cancer and implications for successful early detection in high-risk individuals
KA Overbeek, MG Goggins, M Dbouk, IJM Levink… - Gastroenterology, 2022 - Elsevier
Background & Aims To successfully implement imaging-based pancreatic cancer (PC)
surveillance, understanding the timeline and morphologic features of neoplastic progression …
surveillance, understanding the timeline and morphologic features of neoplastic progression …
Familial pancreatic cancer
H Saba, M Goggins - Gastroenterology Clinics, 2022 - gastro.theclinics.com
Pancreatic ductal adenocarcinoma (PDAC) is the deadliest of all major cancer types with
most patients having advanced disease at diagnosis. Recent data from the National Cancer …
most patients having advanced disease at diagnosis. Recent data from the National Cancer …
MNX1-HNF1B axis is indispensable for intraductal papillary mucinous neoplasm lineages
H Kato, K Tateishi, H Fujiwara, T Nakatsuka… - Gastroenterology, 2022 - Elsevier
Background & Aims Chromatin architecture governs cell lineages by regulating the specific
gene expression; however, its role in the diversity of cancer development remains unknown …
gene expression; however, its role in the diversity of cancer development remains unknown …
Mutant GNAS limits tumor aggressiveness in established pancreatic cancer via antagonizing the KRAS-pathway
H Kawabata, Y Ono, N Tamamura, K Oyama… - Journal of …, 2022 - Springer
Background Mutations in GNAS drive pancreatic tumorigenesis and frequently occur in
intraductal papillary mucinous neoplasm (IPMN); however, their value as a therapeutic …
intraductal papillary mucinous neoplasm (IPMN); however, their value as a therapeutic …
[HTML][HTML] The genetic landscape of pancreatic head ductal adenocarcinoma in China and prognosis stratification
Y Yang, Y Ding, Y Gong, S Zhao, M Li, X Li, G Song… - BMC cancer, 2022 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) is the major subtype of pancreatic
cancer and head PDACs show distinct characteristics from body/tail PDACs. With limited …
cancer and head PDACs show distinct characteristics from body/tail PDACs. With limited …
Comprehensive analysis of molecular biologic characteristics of pancreatic ductal adenocarcinoma concomitant with intraductal papillary mucinous neoplasm
M Tsujimae, A Masuda, T Ikegawa, T Tanaka… - Annals of Surgical …, 2022 - Springer
Background Pancreatic ductal adenocarcinoma (PDAC) concomitant with intraductal
papillary mucinous neoplasm (IPMN) is defined as PDAC occurring apart from IPMN. This …
papillary mucinous neoplasm (IPMN) is defined as PDAC occurring apart from IPMN. This …
[HTML][HTML] Integrative characterization of intraductal tubulopapillary neoplasm (ITPN) of the pancreas and associated invasive adenocarcinoma
Pancreatic intraductal tubulopapillary neoplasm (ITPN) is a recently recognized intraductal
neoplasm. This study aimed to clarify the clinicopathologic and molecular features of this …
neoplasm. This study aimed to clarify the clinicopathologic and molecular features of this …
The impact of clinical and pathological features on intraductal papillary mucinous neoplasm recurrence after surgical resection: long-term follow-up analysis
MJ Pflüger, JF Griffin, WM Hackeng… - Annals of …, 2022 - journals.lww.com
Objective: This study aimed to identify risk factors for recurrence after pancreatic resection
for intraductal papillary mucinous neoplasm (IPMN). Summary Background Data: Long-term …
for intraductal papillary mucinous neoplasm (IPMN). Summary Background Data: Long-term …
Pancreatic cystic neoplasms
S Coban, O Basar, WR Brugge - Gastroenterology Clinics, 2022 - gastro.theclinics.com
A cystic lesion of the pancreas can be caused by various conditions, including cystic
neoplasm, a non-neoplastic cyst, or a solid tumor with cystic degeneration. Histologically …
neoplasm, a non-neoplastic cyst, or a solid tumor with cystic degeneration. Histologically …