[HTML][HTML] Pulmonary immune dysregulation and viral persistence during HIV infection

Y Alexandrova, CT Costiniuk, MA Jenabian - Frontiers in immunology, 2022 - frontiersin.org
Despite the success of antiretroviral therapy (ART), people living with HIV continue to suffer
from high burdens of respiratory infections, lung cancers and chronic lung disease at a …

[HTML][HTML] Tuning Rex rules HTLV-1 pathogenesis

K Nakano, T Watanabe - Frontiers in Immunology, 2022 - frontiersin.org
HTLV-1 is an oncovirus causing ATL and other inflammatory diseases such as HAM/TSP
and HU in about 5% of infected individuals. It is also known that HTLV-1-infected cells …

[HTML][HTML] Increased Prevalence of Unstable HLA-C Variants in HIV-1 Rapid-Progressor Patients

C Stefani, A Sangalli, E Locatelli, T Federico… - International Journal of …, 2022 - mdpi.com
HIV-1 infection in the absence of treatment results in progression toward AIDS. Host genetic
factors play a role in HIV-1 pathogenesis, but complete knowledge is not yet available. Since …

Complement receptor 3 mediates HIV-1 transcytosis across an intact cervical epithelial cell barrier: new insight into HIV transmission in women

CJ Day, RL Hardison, BL Spillings, J Poole… - Mbio, 2022 - Am Soc Microbiol
Transmission of HIV across the mucosal surface of the female reproductive tract to engage
subepithelial CD4-positive T cells is not fully understood. Cervical epithelial cells express …

The Role of Physical Activity on Neurocognitive Function in Diverse Older Persons with HIV (PWH)

AC Summers - 2022 - search.proquest.com
This study was the first to examine the effects of physical activity and cardiorespiratory
function on neurocognitive function among an ethnoculturally diverse group of older people …

HIV-1 Infection Modulates CD4+ T Cell Gene Expression to Induce a Quiescent Phenotype

C Mauer - 2022 - search.proquest.com
The largest barrier to treatment of HIV-1 infection is the establishment of a viral reservoir
constituted mostly by quiescent latently infected CD4+ T cells. This reservoir is formed …

Identification and Analysis of the Heparan Sulfate-Binding Domain and Cellular Factors Involved in the Entry of Human Endogenous Retrovirus K HERV-K (HML-2)

A Ramadan - 2022 - refubium.fu-berlin.de
The human endogenous retroviruses (HERVs) are remnant elements of ancient retroviruses
that infected the human ancestors' germline and integrated into their genome, and thereby …

Compositions and methods for targeted delivery of crispr-cas effector polypeptides and transgenes

JA Doudna, J Hamilton, C Tsuchida - US Patent App. 17/824,626, 2022 - Google Patents
2023-11-16 Assigned to THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
reassignment THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ASSIGNMENT OF …