Hyperdiploidy is the largest genetic entity B-cell precursor acute lymphoblastic leukemia in
children. The diagnostic hallmark of its two variants that will be discussed in detail herein is …

Childhood acute lymphoblastic leukemia (ALL), the most common pediatric cancer, is a
heterogeneous disease comprised of multiple molecular subtypes with distinct somatic …

Introduction Allogeneic hematopoietic stem cell transplantation (HSCT) is widely used for
high-risk acute lymphoblastic leukemia (ALL) patients in their first complete remission (CR1) …

Background B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is a genetically
heterogenous malignancy with poor prognosis in relapsed adult patients. The genetic basis …

Purpose: To analyse the efficacy and safety of rituximab (RTX) in the treatment of children
with steroid-dependent or frequently relapsing nephrotic syndrome (NS). Methods: A total of …

Background: Adopting paediatric-based protocol for adolescent acute lymphoblastic
leukaemia (ALL) patients has been reported leading to superior prognosis, however, large …

A decade of genomic analyses of acute lymphoblastic leukemia (ALL), the commonest
childhood cancer, have transformed our understanding of the genetic basis of B-progenitor …

Acute leukemias are the most commonly diagnosed malignancies in children. Acute
leukemias constitute a heterogeneous group of cancers resulting from clonal outgrowth and …

Aims The aim was to study cytogenetics and molecular genetic profile in pediatric B-acute
lymphoblastic leukemia (ALL) and correlate it with induction outcomes. Subjects and …

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