Psoriasis is an incurable, chronic inflammatory disease, which brings a substantial burden
on individuals and society. Currently, the treatment of psoriasis has entered the era of …

Psoriasis is a common chronic, systemic inflammatory disease, affecting approximately 2%
of the population worldwide. Psoriasis is associated with profound psychosocial comorbidity …

We study high-dimensional bayesian linear regression with product priors. Using the
nascent theory of non-linear large deviations (Chatterjee and Dembo, 2016), we derive …

The skin is the largest barrier organ of the human body and serves to protect the internal
structure of the body from the harmful environment. The epidermis forms the outermost layer …

Background Psoriasis is a systemic chronic inflammatory skin disorder that was prone to
recurrence. The RNA binding protein GNL3 has an important function in maintaining the …

Background: Psoriasis is a common immune-mediated hyperproliferative skin dysfunction
with known genetic predisposition. Gene–gene interaction (eg, between HLA-C and ERAP1) …

Behçet's disease (BD) is a systemic and inflammatory disease, characterized mainly by
recurrent oral and genital ulcers, eye involvement, and skin lesions. Although the exact …

Summary Background Structural variations (SVs; defined as DNA variants≥ 50 base pairs)
have been associated with various complex human diseases. However, research to screen …

Behçet disease (BD) is a polygenic, multifactorial, multisystem inflammatory condition with
unknown etiology. Global distribution of BD is geographically structured, highest prevalence …

Purpose To conduct the first whole exome sequencing (WES) on Takayasu arteritis (TAK) to
identify common and rare variants responsible for disease susceptibility. Patients and …