Tuberculosis screening among HIV-positive inpatients: a systematic review and individual participant data meta-analysis

A Dhana, Y Hamada, AP Kengne, AD Kerkhoff… - The lancet HIV, 2022 - thelancet.com
Background Since 2011, WHO has recommended that HIV-positive inpatients be routinely
screened for tuberculosis with the WHO four-symptom screen (W4SS) and, if screened …

End-point definition and trial design to advance tuberculosis vaccine development

AL Garcia-Basteiro, RG White, D Tait… - European respiratory …, 2022 - Eur Respiratory Soc
Tuberculosis (TB) remains a leading infectious cause of death worldwide and the
coronavirus disease 2019 pandemic has negatively impacted the global TB burden of …

Diagnostic accuracy of WHO screening criteria to guide lateral-flow lipoarabinomannan testing among HIV-positive inpatients: A systematic review and individual …

A Dhana, Y Hamada, AP Kengne, AD Kerkhoff… - Journal of Infection, 2022 - Elsevier
Background WHO recommends urine lateral-flow lipoarabinomannan (LF-LAM) testing with
AlereLAM in HIV-positive inpatients only if screening criteria are met. We assessed the …

Diagnostic value of Lipoarabinomannan antigen for detecting Mycobacterium tuberculosis in adults and children with or without HIV infection

X Yin, QQ Ye, KF Wu, JY Zeng, NX Li… - Journal of Clinical …, 2022 - Wiley Online Library
Objectives Even today, tuberculosis (TB) remains a leading public health problem; yet, the
current diagnostic methods still have a few shortcomings. Lipoarabinomannan (LAM) …

[HTML][HTML] Implementing advanced HIV disease care for inpatients in a Referral Hospital in Malawi–demand, results and cost implications

T Heller, D Damba, T Kumwenda, J Huwa… - Annals of Global …, 2022 - ncbi.nlm.nih.gov
Setting: 100 bed medical ward in referral hospital, Lilongwe, Malawi. Objective: HIV positive
patients admitted to hospital often have advanced HIV disease (AHD) and are at risk for …

Uptake of the lateral flow urine LAM test in Europe and Central Asia

C Kraef, A Yedilbayev, N Seguy… - … of Tuberculosis and …, 2022 - ingentaconnect.com
INTRODUCTION: Since 2015 (updated in 2019), the WHO has recommended to include the
commercial lateral flow urine lipoarabinomannan TB test (LF-LAM), AlereLAM, in the …

Utility of the lateral flow urine lipoarabinomannan tuberculosis assay in patients with advanced HIV disease at antiretroviral therapy centres in Mumbai, India

S Acharya, P Deshpande, ES Asirvatham, A Palkar… - Plos one, 2022 - journals.plos.org
Background People with Advanced HIV Disease (AHD) are at higher risk of TB coinfection
and mortality. However, there are challenges in TB diagnosis with the currently …

[HTML][HTML] FujiLAM for the diagnosis of childhood tuberculosis: a systematic review

L Olbrich, N Khambati, EM Bijker, M Ruhwald… - BMJ paediatrics …, 2022 - ncbi.nlm.nih.gov
Background Childhood tuberculosis (TB) remains underdiagnosed. The novel lateral flow
FujiLAM assay detects lipoarabinomannan (LAM) in urine, but data on performance in …

[HTML][HTML] Xpert MTB/RIF on urine samples to increase diagnosis of TB in people living with HIV in Guinea-Bissau

A Dutschke, D Steiniche, S Jespersen… - International Journal of …, 2022 - Elsevier
Abstract Objectives We investigated if Xpert MTB/RIF (Xpert) testing on urine samples
among newly diagnosed HIV-patients as an adjunctive test to Xpert testing on sputum …

Diagnostic accuracy of urine lipoarabinomannan testing in early morning urine versus spot urine for diagnosis of tuberculosis among people with HIV

S Bjerrum, J Åhsberg, R Szekely, J Opintan… - Microbiology …, 2022 - Am Soc Microbiol
ABSTRACT The Fujifilm SILVAMP TB LAM (FujiLAM) assay offers improved sensitivity
compared to Determine TB LAM Ag (AlereLAM) for detecting tuberculosis (TB) among …