Skeletal muscle atrophy is the consequence of protein degradation exceeding protein
synthesis because of disease, aging, and physical inactivity. Patients with skeletal muscle …

Ischemia‐reperfusion injury (IRI) refers to a syndrome in which tissue damage is further
aggravated and organ function further deteriorates when blood flow is restored after a period …

As one of the hallmarks of cancer, metabolic reprogramming leads to cancer progression,
and targeting glycolytic enzymes could be useful strategies for cancer therapy. By screening …

Breast cancer is the second most common cancer in women. The roles of the SIRT and
FoxO proteins in tumor progression are known, but their roles in metastasis have not yet …

Renal transplantation is currently the most effective treatment for end-stage renal disease.
However, chronic antibody-mediated rejection (cABMR) remains a serious obstacle for the …

Ethnopharmacological relevance Liver fibrosis is a chronic liver disease that can lead to
cirrhosis, liver failure, and hepatocellular carcinoma, and it is associated with long-term …

Pearl oyster (Pinctada fucata) is an economically valuable shellfish for seawater pearl
production. However, many pearl oysters are dying as the global climate warms and …

Background Gastric cancer (GC) is a common type of gastrointestinal tumor in the world.
Transfer RNA (tRNA) derived fragments (tsRNAs) implicate various cancers, but their roles …

Aging is a natural process accompanied by inflammation and oxidative stress and is closely
associated with age-related diseases. As a direct precursor of glutathione, γ …

Background Radioresistance is a major cause of treatment failure in esophageal squamous
cell carcinoma (ESCC) radiotherapy, and the underlying mechanisms of radioresistance are …