The extracellular matrix (ECM) is an important component of the tumor microenvironment
(TME), having several important roles related to the hallmarks of cancer. In cancer, multiple …

Simple Summary Tumor cells struggle to survive following treatment. The struggle ends in
either of two ways. The drug combination used for the treatment blocks the proliferation of …

Neuroblastoma (NB) is an enigmatic and deadliest pediatric cancer to treat. The major
obstacles to the effective immunotherapy treatments in NB are defective immune cells and …

Colorectal cancer (CRC) is one of the most common malignant tumors in the world, and
most colorectal cancer is transformed from colorectal adenoma (CRA). Identifying …

Cartilage oligomeric matrix protein (COMP) is an emerging regulator of tumor progression.
The aim of this study was to evaluate the expression of COMP in periampullary …

The tumor microenvironment (TME) has been shown to be involved in angiogenesis, tumor
metastasis, and immune response, thereby affecting the treatment and prognosis of patients …

Background: Our aim was to explore relevance of the proportion between neoplastic cell
component and tumor-associated stroma in order to assess its association with confirmed …

Tumor-Stroma Ratio, a marker of tumor microenvironment, proved to be a reliable
independent prognostic predictor in many solid tumors but it's value in transitional …

In tumor cells' struggle for survival following therapy, they resist treatment. Resistance to
therapy is the outcome of well-planned, highly efficient adaptive strategies initiated and …

Background: Researches have shown that tumor microenvironment (TME) can regulate the
proliferation and metastasis of solid tumors, and has an important impact on the …