Engineering mesoporous silica nanoparticles for drug delivery: where are we after two decades?
The present review details a chronological description of the events that took place during
the development of mesoporous materials, their different synthetic routes and their use as …
the development of mesoporous materials, their different synthetic routes and their use as …
[Retracted] U‐Net‐Based Medical Image Segmentation
Deep learning has been extensively applied to segmentation in medical imaging. U‐Net
proposed in 2015 shows the advantages of accurate segmentation of small targets and its …
proposed in 2015 shows the advantages of accurate segmentation of small targets and its …
Polyprodrug nanomedicines: an emerging paradigm for cancer therapy
Nanomedicines have the potential to provide advanced therapeutic strategies in combating
tumors. Polymer‐prodrug‐based nanomedicines are particularly attractive in cancer …
tumors. Polymer‐prodrug‐based nanomedicines are particularly attractive in cancer …
[HTML][HTML] Towards principled design of cancer nanomedicine to accelerate clinical translation
Nanotechnology in medical applications, especially in oncology as drug delivery systems,
has recently shown promising results. However, although these advances have been …
has recently shown promising results. However, although these advances have been …
Recent advances in drug delivery and targeting to the brain
Our body keeps separating the toxic chemicals in the blood from the brain. A significant
number of drugs do not enter the central nervous system (CNS) due to the blood-brain …
number of drugs do not enter the central nervous system (CNS) due to the blood-brain …
CD47‐ and Integrin α4/β1‐Comodified‐Macrophage‐Membrane‐Coated Nanoparticles Enable Delivery of Colchicine to Atherosclerotic Plaque
Y Li, J Che, L Chang, M Guo, X Bao… - Advanced …, 2022 - Wiley Online Library
Atherosclerosis is a chronic inflammatory disease and the major pathological factor of most
cardiovascular diseases, leading to≈ 1/3 of deaths worldwide. Improving local delivery of …
cardiovascular diseases, leading to≈ 1/3 of deaths worldwide. Improving local delivery of …
Dual affinity to RBCs and target cells (DART) enhances both organ-and cell type-targeting of intravascular nanocarriers
LT Ferguson, ED Hood, T Shuvaeva, VV Shuvaev… - ACS …, 2022 - ACS Publications
A long-standing goal of nanomedicine is to improve a drug's benefit by loading it into a
nanocarrier that homes solely to a specific target cell and organ. Unfortunately, nanocarriers …
nanocarrier that homes solely to a specific target cell and organ. Unfortunately, nanocarriers …
Inducible endothelial leakiness in nanotherapeutic applications
All intravenous delivered nanomedicine needs to escape from the blood vessel to exert their
therapeutic efficacy at their designated site of action. Failure to do so increases the …
therapeutic efficacy at their designated site of action. Failure to do so increases the …
Precision nanotoxicology in drug development: Current trends and challenges in safety and toxicity implications of customized multifunctional nanocarriers for drug …
The dire need for the assessment of human and environmental endangerments of
nanoparticulate material has motivated the formulation of novel scientific tools and …
nanoparticulate material has motivated the formulation of novel scientific tools and …
[HTML][HTML] Safe and efficient 2D molybdenum disulfide platform for cooperative imaging-guided photothermal-selective chemotherapy: A preclinical study
Introduction The striking imbalance between the ever-increasing amount of nanomedicines
and low clinical translation of products has become the focus of intense debate. For clinical …
and low clinical translation of products has become the focus of intense debate. For clinical …