[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …
commercial point of view. In order to reach the systemic circulation after oral administration …
[HTML][HTML] Mucosa-interfacing electronics
The surface mucosa that lines many of our organs houses myriad biometric signals and,
therefore, has great potential as a sensor–tissue interface for high-fidelity and long-term …
therefore, has great potential as a sensor–tissue interface for high-fidelity and long-term …
Surface modification of lipid-based nanoparticles
There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …
purposes, including the recent increase of these nanocarriers as vaccine components …
[HTML][HTML] Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems
DA Subramanian, R Langer, G Traverso - Journal of nanobiotechnology, 2022 - Springer
Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …
administration which is associated with greater patient medication adherence. One major …
Mucus Penetrating and Cell‐Binding Polyzwitterionic Micelles as Potent Oral Nanomedicine for Cancer Drug Delivery
Orally administrable anticancer nanomedicines are highly desirable due to their easy and
repeatable administration, but are not yet feasible because the current nanomedicine cannot …
repeatable administration, but are not yet feasible because the current nanomedicine cannot …
Advances and future perspectives in epithelial drug delivery
Epithelial surfaces protect exposed tissues in the body against intrusion of foreign materials,
including xenobiotics, pollen and microbiota. The relative permeability of the various …
including xenobiotics, pollen and microbiota. The relative permeability of the various …
Untangling mucosal drug delivery: engineering, designing, and testing nanoparticles to overcome the mucus barrier
J Watchorn, AJ Clasky, G Prakash… - ACS Biomaterials …, 2022 - ACS Publications
Mucus is a complex viscoelastic gel and acts as a barrier covering much of the soft tissue in
the human body. High vascularization and accessibility have motivated drug delivery to …
the human body. High vascularization and accessibility have motivated drug delivery to …
Chitosan-based oral colon-specific delivery systems for polyphenols: recent advances and emerging trends
Oral colon-targeted delivery systems (OCDSs) have attracted great attention in the delivery
of active compounds targeted to the colon for the treatment of colon and non-colon diseases …
of active compounds targeted to the colon for the treatment of colon and non-colon diseases …
[HTML][HTML] Mucus-penetrating silk fibroin-based nanotherapeutics for efficient treatment of ulcerative colitis
D Xie, X Zhou, B Xiao, L Duan, Z Zhu - Biomolecules, 2022 - mdpi.com
Oral nanoparticles have been considered a prospective drug delivery carrier against
ulcerative colitis (UC). To enhance the mucus-penetrating capacity and aqueous solubility …
ulcerative colitis (UC). To enhance the mucus-penetrating capacity and aqueous solubility …
[HTML][HTML] Advancements in rectal drug delivery systems: clinical trials, and patents perspective
The rectal route is an effective route for the local and systemic delivery of active
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …