Global epidemiology of rheumatoid arthritis

A Finckh, B Gilbert, B Hodkinson, SC Bae… - Nature Reviews …, 2022 - nature.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease that predominantly affects the
joints. The prevalence of RA varies globally, with generally a higher prevalence in …

mRNA-based therapeutics: powerful and versatile tools to combat diseases

S Qin, X Tang, Y Chen, K Chen, N Fan… - Signal transduction and …, 2022 - nature.com
The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …

Global incidence, prevalence, and mortality of type 1 diabetes in 2021 with projection to 2040: a modelling study

GA Gregory, TIG Robinson, SE Linklater… - The lancet Diabetes & …, 2022 - thelancet.com
Background Accurate data on type 1 diabetes prevalence, incidence, associated mortality
and life expectancy are crucial to inform public health policy, but these data are scarce. We …

Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

BS Sheena, L Hiebert, H Han, H Ippolito… - The lancet …, 2022 - thelancet.com
Background Combating viral hepatitis is part of the UN Sustainable Development Goals
(SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector …

Depression in young people

A Thapar, O Eyre, V Patel, D Brent - The Lancet, 2022 - thelancet.com
Depression rates in young people have risen sharply in the past decade, especially in
females, which is of concern because adolescence is a period of rapid social, emotional …

2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and …

Authors/Task Force Members:… - European journal of …, 2022 - Wiley Online Library
Abstract Document Reviewers: Rudolf A. de Boer (CPG Review Coordinator)(Netherlands),
P. Christian Schulze (CPG Review Coordinator)(Germany), Magdy Abdelhamid (Egypt) …

Global burden of heart failure: a comprehensive and updated review of epidemiology

G Savarese, PM Becher, LH Lund… - Cardiovascular …, 2022 - academic.oup.com
Heart Failure (HF) is a multi-faceted and life-threatening syndrome characterized by
significant morbidity and mortality, poor functional capacity and quality of life, and high costs …

Telomere dysfunction in ageing and age-related diseases

F Rossiello, D Jurk, JF Passos… - Nature cell …, 2022 - nature.com
Ageing organisms accumulate senescent cells that are thought to contribute to body
dysfunction. Telomere shortening and damage are recognized causes of cellular …

Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2019

X Li, X Feng, X Sun, N Hou, F Han… - Frontiers in Aging …, 2022 - frontiersin.org
Background With the increase in the aging population worldwide, Alzheimer's disease has
become a rapidly increasing public health concern. Monitoring the dementia disease burden …

Burden of chronic obstructive pulmonary disease and its attributable risk factors in 204 countries and territories, 1990-2019: results from the Global Burden of Disease …

S Safiri, K Carson-Chahhoud, M Noori… - Bmj, 2022 - bmj.com
Objective To report the global, regional, and national burden of chronic obstructive
pulmonary disease (COPD) and its attributable risk factors between 1990 and 2019, by age …