Intracellular molecular targets and signaling pathways involved in antioxidative and neuroprotective effects of cannabinoids in neurodegenerative conditions

A Tadijan, I Vlašić, J Vlainić, D Đikić, N Oršolić… - Antioxidants, 2022 - mdpi.com
In the last few decades, endocannabinoids, plant-derived cannabinoids and synthetic
cannabinoids have received growing interest as treatment options in neurodegenerative …

[HTML][HTML] Synaptic changes induced by cannabinoid drugs and cannabis use disorder

SM Augustin, DM Lovinger - Neurobiology of Disease, 2022 - Elsevier
The legalization of cannabis in many countries, as well as the decrease in perceived risks of
cannabis, have contributed to the increase in cannabis use medicinally and recreationally …

[HTML][HTML] The synaptic interactions of alcohol and the endogenous cannabinoid system

SA Wolfe, V Vozella, M Roberto - Alcohol research: current reviews, 2022 - ncbi.nlm.nih.gov
PURPOSE A growing body of evidence has implicated the endocannabinoid (eCB) system
in the acute, chronic, and withdrawal effects of alcohol/ethanol on synaptic function. These …

The endocannabinoid system in the adipose organ

KM Jung, L Lin, D Piomelli - Reviews in Endocrine and Metabolic …, 2022 - Springer
The endocannabinoid system is found in most, if not all, mammalian organs and is involved
in a variety of physiological functions, ranging from the control of synaptic plasticity in the …

Cellular and behavioral basis of cannabinioid and opioid interactions: implications for opioid dependence and withdrawal

A Mohammadkhani, SL Borgland - Journal of Neuroscience …, 2022 - Wiley Online Library
The brain's endogenous opioid and endocannabinoid systems are neuromodulatory of
synaptic transmission, and play key roles in pain, memory, reward, and addiction. Recent …

Electrophysiological study of the interactive role of the cannabinoid breakdown inhibitors and L-type calcium channels on granular neurons in the hippocampal …

SA Karimi, F Kazemi, H Komaki… - Neurological …, 2022 - Taylor & Francis
The interaction between L-type voltage-dependent Ca2+ channels and the
endocannabinoid system (eCs) in synaptic plasticity is controversial. In the present research …

Prefrontal cortical distribution of muscarinic M2 and cannabinoid-1 (CB1) receptors in adult male mice with or without chronic adolescent exposure to Δ9 …

M Garzón, J Chan, K Mackie, VM Pickel - Cerebral Cortex, 2022 - academic.oup.com
Chronic adolescent administration of marijuana's major psychoactive compound,∆ 9-
tetrahydrocannabinol (Δ9-THC), produces adaptive changes in adult social and cognitive …

Mixed effects and mechanisms of cannabinoids for triple-negative breast cancer treatment

K Tran - Herbal Medicines, 2022 - Elsevier
Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by the lack
of estrogen receptors, progesterone receptors, and HER-2 receptors. Thus, TNBC tumors do …

[PDF][PDF] Behavioural and microglial effect of cannabinoids in neuropathic pain

CED Davidson - 2022 - prism.ucalgary.ca
Chronic pain is a disease affecting 1 in 5 Canadians1 and the leading cause of disability
worldwide2. Among the most debilitating forms of chronic pain is neuropathic pain, which is …

A functional endocannabinoid system in human induced pluripotent stem cell-derived cortical cultures

MJ Asher - 2022 - search.proquest.com
The endocannabinoid system is an increasingly popular therapeutic target in many
neurological conditions, due in large part to its ability to protect neurons from damage …