[HTML][HTML] Therapeutic approaches for the treatment of head and neck squamous cell carcinoma–An update on clinical trials
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common non-skin
cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) …
cancer with a tobacco consumption and infection with high-risk human papillomavirus (HPV) …
Novel systemic treatment modalities including immunotherapy and molecular targeted therapy for recurrent and metastatic head and neck squamous cell carcinoma
Head and neck squamous cell carcinomas (HNSCCs) are the sixth most common cancers
worldwide. More than half of patients with HNSCC eventually experience disease …
worldwide. More than half of patients with HNSCC eventually experience disease …
Current status and perspective of tumor immunotherapy for head and neck squamous cell carcinoma
Head and neck squamous cell carcinoma (HNSCC) have a high incidence and mortality
rate, and investigating the pathogenesis and potential therapeutic strategies of HNSCC is …
rate, and investigating the pathogenesis and potential therapeutic strategies of HNSCC is …
Validating a membership disclosure metric for synthetic health data
Background One of the increasingly accepted methods to evaluate the privacy of synthetic
data is by measuring the risk of membership disclosure. This is a measure of the F1 …
data is by measuring the risk of membership disclosure. This is a measure of the F1 …
Radiotherapy, chemotherapy and immunotherapy—current practice and future perspectives for recurrent/metastatic oral cavity squamous cell carcinoma
C Melo-Alvim, ME Neves, JL Santos… - Diagnostics, 2022 - mdpi.com
Oral squamous cell carcinoma is the most common malignant epithelial neoplasm affecting
the oral cavity. While surgical resection is the cornerstone of a multimodal curative …
the oral cavity. While surgical resection is the cornerstone of a multimodal curative …
[HTML][HTML] Efficacy of cetuximab plus PD-1 inhibitor differs by HPV status in head and neck squamous cell carcinoma: a systematic review and meta-analysis
S Zhang, M Zheng, D Nie, L Xu, H Tian… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background The addition of cetuximab significantly increased the antitumor effect of
programmed cell death protein 1 (PD-1) inhibitors in recurrent or metastatic head and neck …
programmed cell death protein 1 (PD-1) inhibitors in recurrent or metastatic head and neck …
Engineering a single-chain variable fragment of cetuximab for CAR T-cell therapy against head and neck squamous cell carcinomas
C Haist, Z Poschinski, A Bister, MJ Hoffmann… - Oral Oncology, 2022 - Elsevier
The monoclonal antibody cetuximab recognizes domain III of the epithelial growth factor
receptor (EGFR) with high-affinity and is an important element in the treatment of several …
receptor (EGFR) with high-affinity and is an important element in the treatment of several …
Engaging innate immunity for targeting the epidermal growth factor receptor: Therapeutic options leveraging innate immunity versus adaptive immunity versus …
G Hintzen, HJ Dulat, E Rajkovic - Frontiers in Oncology, 2022 - frontiersin.org
The epidermal growth factor receptor (EGFR) is a key player in the normal tissue physiology
and the pathology of cancer. Therapeutic approaches have now been developed to target …
and the pathology of cancer. Therapeutic approaches have now been developed to target …
Finding the right heavy chains for immunostimulatory antibodies
P Boulard, V Gouilleux-Gruart, H Watier - International Journal of …, 2022 - mdpi.com
For twelve years, the oncology field has been revolutionized by antibodies targeting immune
checkpoints. They must be considered as a heterogenous family of immunostimulatory …
checkpoints. They must be considered as a heterogenous family of immunostimulatory …
Targeting epidermal growth factor receptor in head and neck cancer
A Bhatia - The Cancer Journal, 2022 - journals.lww.com
Head and neck squamous cell carcinomas are rising in incidence worldwide, and despite
the advent of improved surgical and radiation techniques, a substantial proportion of …
the advent of improved surgical and radiation techniques, a substantial proportion of …