Molecular mechanisms of spontaneous curvature and softening in complex lipid bilayer mixtures

HJ Lessen, KC Sapp, AH Beaven, R Ashkar, AJ Sodt - Biophysical Journal, 2022 - cell.com
Membrane reshaping is an essential biological process. The chemical composition of lipid
membranes determines their mechanical properties and thus the energetics of their shape …

Curvature-based sorting of eight lipid types in asymmetric buckled plasma membrane models

EA Cino, DP Tieleman - Biophysical Journal, 2022 - cell.com
Curvature is a fundamental property of biological membranes and has essential roles in
cellular function. Bending of membranes can be induced by their lipid and protein …

Dynamic cholesterol redistribution favors membrane fusion pore constriction

AH Beaven, K Sapp, AJ Sodt - bioRxiv, 2022 - biorxiv.org
Previous experiments have shown that cholesterol strongly prefers concave leaflets (which
have negative curvature and are typically thin), but cholesterol also orders and thickens …