[HTML][HTML] Oxidative stress in human pathology and aging: molecular mechanisms and perspectives
Reactive oxygen and nitrogen species (RONS) are generated through various endogenous
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …
and exogenous processes; however, they are neutralized by enzymatic and non-enzymatic …
[HTML][HTML] Signaling pathways of chronic kidney diseases, implications for therapeutics
Q Yuan, B Tang, C Zhang - Signal transduction and targeted therapy, 2022 - nature.com
Chronic kidney disease (CKD) is a chronic renal dysfunction syndrome that is characterized
by nephron loss, inflammation, myofibroblasts activation, and extracellular matrix (ECM) …
by nephron loss, inflammation, myofibroblasts activation, and extracellular matrix (ECM) …
[HTML][HTML] Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress …
D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …
[HTML][HTML] The role of oxidative stress in skeletal muscle myogenesis and muscle disease
D Lian, MM Chen, H Wu, S Deng, X Hu - Antioxidants, 2022 - mdpi.com
The contractile activity, high oxygen consumption and metabolic rate of skeletal muscle
cause it to continuously produce moderate levels of oxidant species, such as reactive …
cause it to continuously produce moderate levels of oxidant species, such as reactive …
[HTML][HTML] Vaccination in patients with kidney failure: lessons from COVID-19
Infection is the second leading cause of death in patients with chronic kidney disease (CKD).
Adequate humoral (antibody) and cellular (T cell-driven) immunity are required to minimize …
Adequate humoral (antibody) and cellular (T cell-driven) immunity are required to minimize …
[HTML][HTML] The functions and roles of sestrins in regulating human diseases
Y Chen, T Huang, Z Yu, Q Yu, Y Wang, J Hu… - Cellular & Molecular …, 2022 - Springer
Sestrins (Sesns), highly conserved stress-inducible metabolic proteins, are known to protect
organisms against various noxious stimuli including DNA damage, oxidative stress …
organisms against various noxious stimuli including DNA damage, oxidative stress …
[HTML][HTML] GlyNAC (glycine and N-acetylcysteine) supplementation in mice increases length of life by correcting glutathione deficiency, oxidative stress, mitochondrial …
P Kumar, OW Osahon, RV Sekhar - Nutrients, 2022 - mdpi.com
Determinants of length of life are not well understood, and therefore increasing lifespan is a
challenge. Cardinal theories of aging suggest that oxidative stress (OxS) and mitochondrial …
challenge. Cardinal theories of aging suggest that oxidative stress (OxS) and mitochondrial …
Effects of air pollution on human health–mechanistic evidence suggested by in vitro and in vivo modelling
Airborne particulate matter (PM) comprises both solid and liquid particles, including carbon,
sulphates, nitrate, and toxic heavy metals, which can induce oxidative stress and …
sulphates, nitrate, and toxic heavy metals, which can induce oxidative stress and …
[HTML][HTML] Carotenoids in human skin in vivo: Antioxidant and photo-protectant role against external and internal stressors
ME Darvin, J Lademann, J von Hagen, SB Lohan… - Antioxidants, 2022 - mdpi.com
The antioxidant system of the human body plays a crucial role in maintaining redox
homeostasis and has an important protective function. Carotenoids have pronounced …
homeostasis and has an important protective function. Carotenoids have pronounced …
Recent advances in nanogold as a promising nanocarrier for curcumin delivery
Curcumin is a natural polyphenolic compound that has promising therapeutic benefits.
However, curcumin suffers from low aqueous solubility and poor bioavailability following …
However, curcumin suffers from low aqueous solubility and poor bioavailability following …