The glycocalyx as a permeability barrier: basic science and clinical evidence

RO Dull, RG Hahn - Critical Care, 2022 - Springer
Preclinical studies in animals and human clinical trials question whether the endothelial
glycocalyx layer is a clinically important permeability barrier. Glycocalyx breakdown …

[HTML][HTML] Resuscitation fluids as drugs: targeting the endothelial glycocalyx

G Wang, H Zhang, D Liu, X Wang - Chinese Medical Journal, 2022 - journals.lww.com
Fluid resuscitation is an essential intervention in critically ill patients, and its ultimate goal is
to restore tissue perfusion. Critical illnesses are often accompanied by glycocalyx …

Leveraging avidin-biotin interaction to quantify permeability property of microvessels-on-a-chip networks

F Gao, H Sun, X Li, P He - American Journal of Physiology …, 2022 - journals.physiology.org
Microvessels-on-a-chip have enabled in vitro studies to closely simulate in vivo microvessel
environment. However, assessing microvessel permeability, a functional measure of …

No association between intravenous fluid volume and endothelial glycocalyx shedding in patients undergoing resuscitation for sepsis in the emergency department

S Macdonald, E Bosio, NI Shapiro, L Balmer… - Scientific Reports, 2022 - nature.com
Endothelial glycocalyx (EG) shedding is associated with septic shock and described
following intravenous (IV) fluid administration. To investigate the possible impact of IV fluids …

Induction of endothelial barrier dysfunction by serum factors in rats subjected to traumatic brain injury and hemorrhagic shock

Y Ke, JL Proctor, C Zhang, J Medina… - Physiological …, 2022 - Wiley Online Library
Traumatic brain injury (TBI) has been associated with the development of indirect acute
respiratory distress syndrome (ARDS). However, the causative relationship between TBI and …

Scoring the capillary leak syndrome: towards an individualized gradation of the vascular barrier injury

T Belveyre, C Ince, P Guerci - Annals of intensive care, 2022 - Springer
Wollborn et al. nicely described a new scoring system for non-invasive detection of capillary
leakage in critically ill patients [1]. The authors are commended for their efforts in elucidating …

[HTML][HTML] Deconstructing Organs: Single-Cell Analyses, Decellularized Organs, Organoids, and Organ-on-a-Chip Models: Leveraging avidin-biotin interaction to …

F Gao, H Sun, X Li, P He - American Journal of Physiology-Heart …, 2022 - ncbi.nlm.nih.gov
Microvessels-on-a-chip have enabled in vitro studies to closely simulate in vivo microvessel
environment. However, assessing microvessel permeability, a functional measure of …

[PDF][PDF] Stephen Macdonald1, 2, 3Ε, Erika Bosio1, 2, Nathan I. Shapiro4, Lois Balmer1, 5, Sally Burrows2, 6

M Hibbs, T Jowitt, L Smart, G Arendts, D Fatovich - Scientific Reports, 2022 - academia.edu
Methods Participants and setting. We undertook secondary analysis of a convenience
sample of adult (age 18 years or older) ED patients undergoing haemodynamic …

An Evaluation of Micro-and Macrocirculatory Perfusion in Horses with Acute Surgical Colic

PW Foth - 2022 - rave.ohiolink.edu
The mammalian circulatory system is divided into the macro-and microcirculation which
together provides blood flow to the organs and tissues of the body. The macrocirculation is …